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A-to-I editing of coding and non-coding RNAs by ADARs

Overview of attention for article published in Nature Reviews Molecular Cell Biology, December 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

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2 news outlets
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11 X users
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4 patents
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7 Facebook pages
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1 Google+ user

Citations

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743 Mendeley
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2 CiteULike
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Title
A-to-I editing of coding and non-coding RNAs by ADARs
Published in
Nature Reviews Molecular Cell Biology, December 2015
DOI 10.1038/nrm.2015.4
Pubmed ID
Authors

Kazuko Nishikura

Abstract

Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA. This A-to-I editing occurs not only in protein-coding regions of mRNAs, but also frequently in non-coding regions that contain inverted Alu repeats. Editing of coding sequences can result in the expression of functionally altered proteins that are not encoded in the genome, whereas the significance of Alu editing remains largely unknown. Certain microRNA (miRNA) precursors are also edited, leading to reduced expression or altered function of mature miRNAs. Conversely, recent studies indicate that ADAR1 forms a complex with Dicer to promote miRNA processing, revealing a new function of ADAR1 in the regulation of RNA interference.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 743 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Slovenia 2 <1%
Canada 2 <1%
Germany 1 <1%
United Kingdom 1 <1%
Israel 1 <1%
Chile 1 <1%
Taiwan 1 <1%
Denmark 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 731 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 169 23%
Researcher 107 14%
Student > Bachelor 106 14%
Student > Master 83 11%
Student > Doctoral Student 32 4%
Other 76 10%
Unknown 170 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 265 36%
Agricultural and Biological Sciences 167 22%
Medicine and Dentistry 32 4%
Chemistry 26 3%
Immunology and Microbiology 25 3%
Other 47 6%
Unknown 181 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2023.
All research outputs
#1,258,237
of 25,837,817 outputs
Outputs from Nature Reviews Molecular Cell Biology
#329
of 2,651 outputs
Outputs of similar age
#20,735
of 400,272 outputs
Outputs of similar age from Nature Reviews Molecular Cell Biology
#3
of 40 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,651 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.4. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,272 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.