Title |
Pathogenetic Role of Endothelial Dysfunction in Idiopathic Vestibulopathy
|
---|---|
Published in |
Bulletin of Experimental Biology and Medicine, April 2018
|
DOI | 10.1007/s10517-018-4067-0 |
Pubmed ID | |
Authors |
E. V. Udut, P. P. Shchetinin, T. V. Rudenko, F. Lucieer, H. Kingma, A. P. Shchetinina, M. O. Pleshkov, V. P. Demkin, V. V. Udut |
Abstract |
Comparative analysis of the groups of patients with idiopathic bilateral vestibular hypofunction and a group of vestibulopathy patients with vertebrobasilar insufficiency demonstrated identity of the basic and additional diagnostic parameters in these syndromes as well as similarity in clinical diagnostic and anamnesis data. In all cases, functional assessment of endothelium-dependent vasodilation and selected biochemical marker sICAM-1 revealed endothelial dysfunction. Drug correction of endothelial dysfunction positively affected the manifestations of major and minor features of the syndrome, which confirmed the contribution of endothelial functional disturbances to the pathogenesis of bilateral vestibular hypofunction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 17% |
Student > Bachelor | 2 | 11% |
Researcher | 2 | 11% |
Student > Master | 2 | 11% |
Professor | 2 | 11% |
Other | 3 | 17% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 4 | 22% |
Medicine and Dentistry | 4 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 11% |
Economics, Econometrics and Finance | 1 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Other | 2 | 11% |
Unknown | 4 | 22% |