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16 T Diffusion microimaging of fixed prostate tissue: Preliminary findings

Overview of attention for article published in Magnetic Resonance in Medicine, February 2011
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Title
16 T Diffusion microimaging of fixed prostate tissue: Preliminary findings
Published in
Magnetic Resonance in Medicine, February 2011
DOI 10.1002/mrm.22778
Pubmed ID
Authors

Roger Bourne, Nyoman Kurniawan, Gary Cowin, Paul Sved, Geoff Watson

Abstract

Diffusion tensor microimaging was used to investigate the water diffusion properties of formalin-fixed prostate tissue at spatial resolution approaching the cellular scale. Diffusion tensor microimaging was performed at 16.4 T with 40 μm isotropic voxels. Diffusion tensor microimaging clearly demonstrated distinct microscopic diffusion environments and tissue architecture consistent with that seen on light microscopy of the same tissue. The most restricted diffusion environment is the secretory epithelial cell layer (voxel bulk mean diffusivity, D = 0.4 ± 0.1 × 10(-3) mm(2)/sec). Diffusion in the fibromuscular stromal matrix is relatively less restricted (D = 0.7 ± 0.1 × 10(-3) mm(2)/sec). In tumor tissue (Gleason pattern 4+4) distinct glandular and ductal structures are absent in the diffusion-weighted images and diffusivity is low (D = 0.5 ± 0.1 × 10(-3) mm(2)/sec). Distinct stromal and epithelial diffusion compartments are the most likely origin of biexponential diffusion decay observed in vivo.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 5%
Japan 1 3%
Germany 1 3%
Unknown 34 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 29%
Other 6 16%
Student > Ph. D. Student 6 16%
Student > Master 4 11%
Student > Bachelor 2 5%
Other 6 16%
Unknown 3 8%
Readers by discipline Count As %
Medicine and Dentistry 10 26%
Engineering 7 18%
Physics and Astronomy 5 13%
Computer Science 4 11%
Agricultural and Biological Sciences 2 5%
Other 3 8%
Unknown 7 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2011.
All research outputs
#16,721,387
of 24,590,593 outputs
Outputs from Magnetic Resonance in Medicine
#5,633
of 7,067 outputs
Outputs of similar age
#152,133
of 192,851 outputs
Outputs of similar age from Magnetic Resonance in Medicine
#86
of 93 outputs
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