| Title |
From miracle fruit to transgenic tomato: mass production of the taste-modifying protein miraculin in transgenic plants
|
|---|---|
| Published in |
Plant Cell Reports, December 2011
|
| DOI | 10.1007/s00299-011-1197-5 |
| Pubmed ID | |
| Authors |
Kyoko Hiwasa-Tanase, Tadayoshi Hirai, Kazuhisa Kato, Narendra Duhita, Hiroshi Ezura |
| Abstract |
The utility of plants as biofactories has progressed in recent years. Some recombinant plant-derived pharmaceutical products have already reached the marketplace. However, with the exception of drugs and vaccines, a strong effort has not yet been made to bring recombinant products to market, as cost-effectiveness is critically important for commercialization. Sweet-tasting proteins and taste-modifying proteins have a great deal of potential in industry as substitutes for sugars and as artificial sweeteners. The taste-modifying protein, miraculin, functions to change the perception of a sour taste to a sweet one. This taste-modifying function can potentially be used not only as a low-calorie sweetener but also as a new seasoning that could be the basis of a new dietary lifestyle. However, miraculin is far from inexpensive, and its potential as a marketable product has not yet been fully developed. For the last several years, biotechnological production of this taste-modifying protein has progressed extensively. In this review, the characteristics of miraculin and recent advances in its production using transgenic plants are summarized, focusing on such topics as the suitability of plant species as expression hosts, the cultivation method for transgenic plants, the method of purifying miraculin and future advances required to achieve industrial use. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 25% |
| Canada | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Cyprus | 1 | <1% |
| Ethiopia | 1 | <1% |
| Indonesia | 1 | <1% |
| United Kingdom | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Argentina | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 94 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 20 | 20% |
| Student > Master | 14 | 14% |
| Researcher | 12 | 12% |
| Student > Postgraduate | 8 | 8% |
| Professor | 8 | 8% |
| Other | 26 | 26% |
| Unknown | 13 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 51 | 50% |
| Biochemistry, Genetics and Molecular Biology | 11 | 11% |
| Medicine and Dentistry | 5 | 5% |
| Chemistry | 5 | 5% |
| Nursing and Health Professions | 2 | 2% |
| Other | 11 | 11% |
| Unknown | 16 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2023.
All research outputs
#1,864,423
of 24,053,881 outputs
Outputs from Plant Cell Reports
#43
of 2,273 outputs
Outputs of similar age
#13,310
of 247,735 outputs
Outputs of similar age from Plant Cell Reports
#1
of 13 outputs
Altmetric has tracked 24,053,881 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,273 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.