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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Accelerating stem cell trials for Alzheimer's disease
|
|---|---|
| Published in |
Lancet Neurology, December 2015
|
| DOI | 10.1016/s1474-4422(15)00332-4 |
| Pubmed ID | |
| Authors |
Joshua G Hunsberger, Mahendra Rao, Joanne Kurtzberg, Jeff W M Bulte, Anthony Atala, Frank M LaFerla, Henry T Greely, Akira Sawa, Sam Gandy, Lon S Schneider, P Murali Doraiswamy |
| Abstract |
At present, no effective cure or prophylaxis exists for Alzheimer's disease. Symptomatic treatments are modestly effective and offer only temporary benefit. Advances in induced pluripotent stem cell (iPSC) technology have the potential to enable development of so-called disease-in-a-dish personalised models to study disease mechanisms and reveal new therapeutic approaches, and large panels of iPSCs enable rapid screening of potential drug candidates. Different cell types can also be produced for therapeutic use. In 2015, the US Food and Drug Administration granted investigational new drug approval for the first phase 2A clinical trial of ischaemia-tolerant mesenchymal stem cells to treat Alzheimer's disease in the USA. Similar trials are either underway or being planned in Europe and Asia. Although safety and ethical concerns remain, we call for the acceleration of human stem cell-based translational research into the causes and potential treatments of Alzheimer's disease. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 42% |
| United Kingdom | 3 | 25% |
| Ireland | 1 | 8% |
| Unknown | 3 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 58% |
| Scientists | 2 | 17% |
| Science communicators (journalists, bloggers, editors) | 2 | 17% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | <1% |
| China | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 187 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 33 | 17% |
| Student > Ph. D. Student | 31 | 16% |
| Student > Bachelor | 22 | 12% |
| Researcher | 22 | 12% |
| Professor | 12 | 6% |
| Other | 29 | 15% |
| Unknown | 41 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 29 | 15% |
| Agricultural and Biological Sciences | 28 | 15% |
| Medicine and Dentistry | 25 | 13% |
| Biochemistry, Genetics and Molecular Biology | 21 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 5% |
| Other | 34 | 18% |
| Unknown | 44 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 35. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2020.
All research outputs
#1,146,796
of 25,374,917 outputs
Outputs from Lancet Neurology
#736
of 4,011 outputs
Outputs of similar age
#18,550
of 380,106 outputs
Outputs of similar age from Lancet Neurology
#16
of 76 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,011 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 34.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 380,106 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.