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Advances in silica based nanoparticles for targeted cancer therapy

Overview of attention for article published in Nanomedicine: Nanotechnology, Biology and Medicine, December 2015
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

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1 X user
patent
1 patent

Citations

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154 Dimensions

Readers on

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214 Mendeley
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Title
Advances in silica based nanoparticles for targeted cancer therapy
Published in
Nanomedicine: Nanotechnology, Biology and Medicine, December 2015
DOI 10.1016/j.nano.2015.10.018
Pubmed ID
Authors

Yannan Yang, Chengzhong Yu

Abstract

Targeted delivery of anticancer drug specifically to tumour site without damaging normal tissues has been the dream of all scientists fighting against cancer for decades. Recent breakthrough on nanotechnology based medicines has provided a possible tool to solve this puzzle. Among diverse nanomaterials that are under development and extensive study, silica based nanoparticles with vast advantages have attracted great attention. In this review, we concentrate on the recent progress using silica based nanoparticles, particularly mesoporous silica nanoparticles (MSNs), for targeted drug delivery applications. Firstly, we discuss the passive targeting capability of silica based nanoparticles in relation to their physiochemical properties. Then, we focus on the recent advances of active targeting strategies involving tumour cell targeting, vascular targeting, nuclear targeting and multistage targeting, followed by an introduction to magnetic field directed targeting approach. We conclude with our personal perspectives on the remaining challenges and the possible future directions.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 214 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 <1%
India 1 <1%
Iran, Islamic Republic of 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 209 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 62 29%
Student > Master 32 15%
Student > Bachelor 29 14%
Researcher 21 10%
Student > Doctoral Student 9 4%
Other 18 8%
Unknown 43 20%
Readers by discipline Count As %
Chemistry 44 21%
Biochemistry, Genetics and Molecular Biology 26 12%
Pharmacology, Toxicology and Pharmaceutical Science 21 10%
Agricultural and Biological Sciences 19 9%
Engineering 16 7%
Other 38 18%
Unknown 50 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2024.
All research outputs
#7,968,106
of 25,394,764 outputs
Outputs from Nanomedicine: Nanotechnology, Biology and Medicine
#458
of 1,520 outputs
Outputs of similar age
#110,245
of 380,268 outputs
Outputs of similar age from Nanomedicine: Nanotechnology, Biology and Medicine
#13
of 76 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,520 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 380,268 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.