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Single‐cell transcriptomes reveal characteristic features of human pancreatic islet cell types

Overview of attention for article published in EMBO Reports, December 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
9 news outlets
blogs
2 blogs
twitter
6 X users
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
204 Dimensions

Readers on

mendeley
304 Mendeley
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Title
Single‐cell transcriptomes reveal characteristic features of human pancreatic islet cell types
Published in
EMBO Reports, December 2015
DOI 10.15252/embr.201540946
Pubmed ID
Authors

Jin Li, Johanna Klughammer, Matthias Farlik, Thomas Penz, Andreas Spittler, Charlotte Barbieux, Ekaterine Berishvili, Christoph Bock, Stefan Kubicek

Abstract

Pancreatic islets of Langerhans contain several specialized endocrine cell types, which are commonly identified by the expression of single marker genes. However, the established marker genes cannot capture the complete spectrum of cellular heterogeneity in human pancreatic islets, and existing bulk transcriptome datasets provide averages across several cell populations. To dissect the cellular composition of the human pancreatic islet and to establish transcriptomes for all major cell types, we performed single-cell RNA sequencing on 70 cells sorted from human primary tissue. We used this dataset to validate previously described marker genes at the single-cell level and to identify specifically expressed transcription factors for all islet cell subtypes. All data are available for browsing and download, thus establishing a useful resource of single-cell expression profiles for endocrine cells in human pancreatic islets.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 304 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Spain 1 <1%
Denmark 1 <1%
Austria 1 <1%
Unknown 300 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 72 24%
Researcher 62 20%
Student > Master 30 10%
Student > Bachelor 29 10%
Student > Doctoral Student 21 7%
Other 55 18%
Unknown 35 12%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 105 35%
Agricultural and Biological Sciences 83 27%
Medicine and Dentistry 37 12%
Engineering 9 3%
Chemistry 5 2%
Other 21 7%
Unknown 44 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 80. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2021.
All research outputs
#541,883
of 26,017,215 outputs
Outputs from EMBO Reports
#124
of 4,117 outputs
Outputs of similar age
#9,029
of 401,993 outputs
Outputs of similar age from EMBO Reports
#3
of 39 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,117 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 401,993 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.