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Propagation and Purification of Ectromelia Virus

Overview of attention for article published in Current protocols in microbiology, October 2018
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Title
Propagation and Purification of Ectromelia Virus
Published in
Current protocols in microbiology, October 2018
DOI 10.1002/cpmc.65
Pubmed ID
Authors

Geeta Chaudhri, Georgina Kaladimou, Pratikshya Pandey, Gunasegaran Karupiah

Abstract

Ectromelia virus (ECTV) is an orthopoxvirus that causes mousepox in mice. Members of the genus orthopoxvirus are closely related and include variola (the causative agent of smallpox in humans), monkeypox, and vaccinia. Common features of variola virus and ECTV further include a restricted host range and similar disease progression in their respective hosts. Mousepox makes an excellent small animal model for smallpox to investigate pathogenesis, vaccine and antiviral agent testing, host-virus interactions, and immune and inflammatory responses. The availability of a wide variety of inbred, congenic, and gene-knockout mice allows detailed analyses of the host response. ECTV mutant viruses lacking one or more genes encoding immunomodulatory proteins are being used in numerous studies in conjunction with wild-type or gene-knockout mice to study the functions of these genes in host-virus interactions. The methods used for propagation of ECTV in cell culture, purification, and quantification of infectious particles through viral plaque assay are described. © 2018 by John Wiley & Sons, Inc.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 14%
Student > Master 2 14%
Librarian 1 7%
Student > Ph. D. Student 1 7%
Professor > Associate Professor 1 7%
Other 1 7%
Unknown 6 43%
Readers by discipline Count As %
Medicine and Dentistry 4 29%
Neuroscience 1 7%
Immunology and Microbiology 1 7%
Unknown 8 57%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2018.
All research outputs
#17,292,294
of 25,385,509 outputs
Outputs from Current protocols in microbiology
#119
of 179 outputs
Outputs of similar age
#227,625
of 354,905 outputs
Outputs of similar age from Current protocols in microbiology
#4
of 7 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 179 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,905 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.