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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
|
|---|---|
| Published in |
Nature Genetics, August 2008
|
| DOI | 10.1038/ng.209 |
| Pubmed ID | |
| Authors |
Manuel A R Ferreira, Michael C O'Donovan, Yan A Meng, Ian R Jones, Douglas M Ruderfer, Lisa Jones, Jinbo Fan, George Kirov, Roy H Perlis, Elaine K Green, Jordan W Smoller, Detelina Grozeva, Jennifer Stone, Ivan Nikolov, Kimberly Chambert, Marian L Hamshere, Vishwajit L Nimgaonkar, Valentina Moskvina, Michael E Thase, Sian Caesar, Gary S Sachs, Jennifer Franklin, Katherine Gordon-Smith, Kristin G Ardlie, Stacey B Gabriel, Christine Fraser, Brendan Blumenstiel, Matthew Defelice, Gerome Breen, Michael Gill, Derek W Morris, Amanda Elkin, Walter J Muir, Kevin A McGhee, Richard Williamson, Donald J MacIntyre, Alan W MacLean, David St Clair, Michelle Robinson, Margaret Van Beck, Ana C P Pereira, Radhika Kandaswamy, Andrew McQuillin, David A Collier, Nicholas J Bass, Allan H Young, Jacob Lawrence, I Nicol Ferrier, Adebayo Anjorin, Anne Farmer, David Curtis, Edward M Scolnick, Peter McGuffin, Mark J Daly, Aiden P Corvin, Peter A Holmans, Douglas H Blackwood, Hugh M Gurling, Michael J Owen, Shaun M Purcell, Pamela Sklar, Nick Craddock |
| Abstract |
To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 x 10(-9)) in ANK3 (ankyrin G). We also found further support for the previously reported CACNA1C (alpha 1C subunit of the L-type voltage-gated calcium channel; combined P = 7.0 x 10(-8), rs1006737). Our results suggest that ion channelopathies may be involved in the pathogenesis of bipolar disorder. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 695 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 2% |
| United Kingdom | 7 | 1% |
| Brazil | 4 | <1% |
| Germany | 2 | <1% |
| Switzerland | 2 | <1% |
| Italy | 2 | <1% |
| Canada | 2 | <1% |
| Netherlands | 2 | <1% |
| France | 1 | <1% |
| Other | 4 | <1% |
| Unknown | 656 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 124 | 18% |
| Student > Bachelor | 106 | 15% |
| Student > Ph. D. Student | 103 | 15% |
| Student > Master | 75 | 11% |
| Professor > Associate Professor | 48 | 7% |
| Other | 138 | 20% |
| Unknown | 101 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 182 | 26% |
| Medicine and Dentistry | 129 | 19% |
| Biochemistry, Genetics and Molecular Biology | 86 | 12% |
| Neuroscience | 69 | 10% |
| Psychology | 53 | 8% |
| Other | 44 | 6% |
| Unknown | 132 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2024.
All research outputs
#1,707,277
of 26,017,215 outputs
Outputs from Nature Genetics
#2,423
of 7,639 outputs
Outputs of similar age
#4,160
of 97,448 outputs
Outputs of similar age from Nature Genetics
#10
of 57 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,639 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.7. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 97,448 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.