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Different osteocalcin forms, markers of metabolic syndrome and anthropometric measures in children within the IDEFICS cohort

Overview of attention for article published in BONE, January 2016
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Title
Different osteocalcin forms, markers of metabolic syndrome and anthropometric measures in children within the IDEFICS cohort
Published in
BONE, January 2016
DOI 10.1016/j.bone.2016.01.008
Pubmed ID
Authors

Bojan Tubic, Per Magnusson, Staffan Mårild, Monica Leu, Verena Schwetz, Isabelle Sioen, Diana Herrmann, Barbara Obermayer-Pietsch, Lauren Lissner, Diana Swolin-Eide, on behalf of the IDEFICS consortium

Abstract

Osteocalcin (OC), an aboundant non-collgenous bone protein, is inversely associated with parameters of glucose metabolism. Interactions between bone tissue and energy metabolism have not been thoroughly investigated during childhood. This study investigated OC, metabolic parameters and anthropometric characteristics in normal weight and overweight/obese children. This study comprised 108 (46 normal weight/62 overweight/obese) Swedish 2-9year old children. Anthropometric data, insulin, glucose, glycosylated haemoglobin (HbA1c), HOMA index, vitamin D, adiponectin, total OC, carboxylated OC (cOC) and undercarboxylated OC (ucOC) were analysed. No difference was found for total OC between the normal and overweight/obese groups, with a mean (±SD) value of 82.6 (±2.8) ng/mL and 77.0 (±2.4) ng/mL, (P=0.11), respectively. Overweight children had lower cOC levels, mean 69.1 (±2.2) ng/mL, vs. normal weight children, mean 75.6 (±2.5) ng/mL (P=0.03). The mean ucOC levels of 7.9 (±0.4) ng/mL in overweight children did not differ vs. normal weight children, mean level 7.0 (±0.4) ng/mL, (P=0.067). None of the three OC forms correlated with any of the measured parameters. The cOC levels were lower in overweight children. There was no correlation between the three OC forms and any of the measured anthropometric or metabolic parameters. OC has been suggested to have a possible metabolic role, but in general the current study in prepubertal children does not support the hypothesis of an association between OC and a positive metabolic profile.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 20%
Other 3 12%
Student > Master 3 12%
Professor 2 8%
Student > Bachelor 1 4%
Other 5 20%
Unknown 6 24%
Readers by discipline Count As %
Medicine and Dentistry 12 48%
Nursing and Health Professions 2 8%
Environmental Science 1 4%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 2 8%
Unknown 6 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2016.
All research outputs
#17,313,103
of 25,411,814 outputs
Outputs from BONE
#2,792
of 4,330 outputs
Outputs of similar age
#242,641
of 400,298 outputs
Outputs of similar age from BONE
#30
of 71 outputs
Altmetric has tracked 25,411,814 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,330 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,298 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.