Title |
Antimutagenic and Anticancer Activity of Al Madinah Alhasawy Mint (<I>Mentha longifolia</I>) Leaves Extract
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Published in |
Pakistan Journal of Biological Sciences, November 2014
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DOI | 10.3923/pjbs.2014.1231.1236 |
Pubmed ID | |
Authors |
Khalil Al-Ali, Mohamad Abdelrazik, Abdulaziz Alghaithy, Atef Diab, Hesham El-Beshbishy, Hussam Baghdadi |
Abstract |
Mentha is one of the genera of Lamiaceae family. The aim of the present study was to evaluate the antimutagenic and anticancer activity of the water and methanolic extract of Alhasawy mint (Mentha longifolia), that grown in Madina Province, western region, Saudi Arabia using three different bioassays namely; Brine shrimp bioassay, Ames mutagenicity bioassay using 3 Hist-Salmonella typhimurium strains of different mutations (TA98, TA97 and TA100) and 2 reference mutagenic drugs nitrosopiperidine (NP) and 2-amino-3-methylimidazo-quinolidine (IQ) and Mammalian cell lines bioassays using 2 different cell lines HepG2 and Vero cell lines. The plant extract showed an efficient antimutagenic activity against the studied bioassays in a directly proportional effect with concentration. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Greece | 1 | 4% |
Unknown | 26 | 96% |
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Student > Ph. D. Student | 7 | 26% |
Student > Bachelor | 3 | 11% |
Other | 2 | 7% |
Student > Master | 2 | 7% |
Student > Postgraduate | 2 | 7% |
Other | 3 | 11% |
Unknown | 8 | 30% |
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Pharmacology, Toxicology and Pharmaceutical Science | 2 | 7% |
Nursing and Health Professions | 1 | 4% |
Computer Science | 1 | 4% |
Other | 4 | 15% |
Unknown | 11 | 41% |