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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Clarifying the Translational Pausing Landscape in Bacteria by Ribosome Profiling
|
|---|---|
| Published in |
Cell Reports, January 2016
|
| DOI | 10.1016/j.celrep.2015.12.073 |
| Pubmed ID | |
| Authors |
Fuad Mohammad, Christopher J. Woolstenhulme, Rachel Green, Allen R. Buskirk |
| Abstract |
The rate of protein synthesis varies according to the mRNA sequence in ways that affect gene expression. Global analysis of translational pausing is now possible with ribosome profiling. Here, we revisit an earlier report that Shine-Dalgarno sequences are the major determinant of translational pausing in bacteria. Using refinements in the profiling method as well as biochemical assays, we find that SD motifs have little (if any) effect on elongation rates. We argue that earlier evidence of pausing arose from two factors. First, in previous analyses, pauses at Gly codons were difficult to distinguish from pauses at SD motifs. Second, and more importantly, the initial study preferentially isolated long ribosome-protected mRNA fragments that are enriched in SD motifs. These findings clarify the landscape of translational pausing in bacteria as observed by ribosome profiling. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 58% |
| United Kingdom | 2 | 17% |
| Egypt | 1 | 8% |
| Ireland | 1 | 8% |
| Unknown | 1 | 8% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 67% |
| Scientists | 3 | 25% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 277 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 1% |
| Brazil | 1 | <1% |
| India | 1 | <1% |
| Canada | 1 | <1% |
| Argentina | 1 | <1% |
| Denmark | 1 | <1% |
| United Kingdom | 1 | <1% |
| Estonia | 1 | <1% |
| China | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 263 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 97 | 35% |
| Researcher | 45 | 16% |
| Student > Master | 29 | 10% |
| Student > Bachelor | 20 | 7% |
| Student > Doctoral Student | 10 | 4% |
| Other | 34 | 12% |
| Unknown | 42 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 109 | 39% |
| Agricultural and Biological Sciences | 82 | 30% |
| Chemistry | 8 | 3% |
| Immunology and Microbiology | 4 | 1% |
| Physics and Astronomy | 4 | 1% |
| Other | 24 | 9% |
| Unknown | 46 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2016.
All research outputs
#5,165,601
of 25,373,627 outputs
Outputs from Cell Reports
#8,095
of 12,956 outputs
Outputs of similar age
#82,297
of 402,343 outputs
Outputs of similar age from Cell Reports
#142
of 262 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,956 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.3. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 402,343 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 262 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.