| Title |
The Orphan Nuclear Receptor TLX/NR2E1 in Neural Stem Cells and Diseases
|
|---|---|
| Published in |
Neuroscience Bulletin, January 2016
|
| DOI | 10.1007/s12264-015-0004-7 |
| Pubmed ID | |
| Authors |
Tao Wang, Jian-Qiong Xiong |
| Abstract |
The human TLX gene encodes an orphan nuclear receptor predominantly expressed in the central nervous system. Tailess and Tlx, the TLX homologues in Drosophila and mouse, play essential roles in body-pattern formation and neurogenesis during early embryogenesis and perform crucial functions in maintaining stemness and controlling the differentiation of adult neural stem cells in the central nervous system, especially the visual system. Multiple target genes and signaling pathways are regulated by TLX and its homologues in specific tissues during various developmental stages. This review aims to summarize previous studies including many recent updates from different aspects concerning TLX and its homologues in Drosophila and mouse. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 28 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 29% |
| Researcher | 4 | 14% |
| Student > Bachelor | 3 | 11% |
| Student > Doctoral Student | 2 | 7% |
| Professor | 2 | 7% |
| Other | 7 | 25% |
| Unknown | 2 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 25% |
| Agricultural and Biological Sciences | 6 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 11% |
| Neuroscience | 3 | 11% |
| Medicine and Dentistry | 3 | 11% |
| Other | 1 | 4% |
| Unknown | 5 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2016.
All research outputs
#18,345,259
of 23,577,654 outputs
Outputs from Neuroscience Bulletin
#460
of 815 outputs
Outputs of similar age
#273,265
of 399,300 outputs
Outputs of similar age from Neuroscience Bulletin
#7
of 11 outputs
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