Title |
Atypical fractures, a biased perspective
|
---|---|
Published in |
Injury, January 2016
|
DOI | 10.1016/s0020-1383(16)30007-9 |
Pubmed ID | |
Authors |
Per Aspenberg |
Abstract |
When stress fractures started to show up in the femurs of elderly ladies, it was soon evident that bisphosphonate use lay behind, and the absolute risk increase due to bisphosphonate use was reasonably well estimated already in 2008. Thereafter followed a period of confusion: the term atypical fracture was introduced, with a definition so vague that the true stress fractures tended to disappear in a cloud of ambiguity. This cast doubt on the association with bisphosphonates. The association was then re-established by large epidemiological studies based on radiographic adjudication. Atypical fractures are largely caused by bisphosphonates. With a correct indication, bisphosphonates prevent many more fractures than they cause, at least during the first years of use. With an incorrect indication they are likely to cause more harm than good. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 3 | 21% |
Lecturer | 2 | 14% |
Student > Master | 2 | 14% |
Other | 1 | 7% |
Professor | 1 | 7% |
Other | 2 | 14% |
Unknown | 3 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 50% |
Nursing and Health Professions | 1 | 7% |
Business, Management and Accounting | 1 | 7% |
Agricultural and Biological Sciences | 1 | 7% |
Engineering | 1 | 7% |
Other | 0 | 0% |
Unknown | 3 | 21% |