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Update of the human parvovirus B19 biology

Overview of attention for article published in Transfusion Clinique et Biologique, January 2016
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Title
Update of the human parvovirus B19 biology
Published in
Transfusion Clinique et Biologique, January 2016
DOI 10.1016/j.tracli.2015.11.006
Pubmed ID
Authors

A. Servant-Delmas, F. Morinet

Abstract

Since its discovery, the human parvovirus B19 (B19V) has been associated with many clinical situations in addition to the prototype clinical manifestations, i.e. erythema infectiosum and erythroblastopenia crisis. The clinical significance of the viral B19V DNA persistence in sera after acute infection remains largely unknown. Such data may constitute a new clinical entity and is discussed in this manuscript. In 2002, despite the genetic diversity among B19V viruses has been reported to be very low, the description of markedly distinct sequences showed a new organization into three genotypes. The most recent common ancestor for B19V genotypes was estimated at early 1800s. B19V replication is enhanced by hypoxia and this might to explain the high viral load detected by quantitative PCR in the sera of infected patients. The minimum infectious dose necessary to transmit B19V infection by the transfusion of labile blood products remains unclear. At the opposite, the US Food and Drug Administration proposed a limit of 10(4)IU/mL of viral DNA in plasma pools used for the production of plasma derivatives. Recently, a new human parvovirus (PARV4) has been discovered. The consequences on blood transfusion of this blood-borne agent and its pathogenicity are still unknown.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 16%
Student > Bachelor 6 12%
Student > Doctoral Student 5 10%
Other 5 10%
Researcher 3 6%
Other 7 14%
Unknown 17 33%
Readers by discipline Count As %
Medicine and Dentistry 11 22%
Biochemistry, Genetics and Molecular Biology 7 14%
Immunology and Microbiology 5 10%
Agricultural and Biological Sciences 4 8%
Veterinary Science and Veterinary Medicine 2 4%
Other 4 8%
Unknown 18 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2016.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Transfusion Clinique et Biologique
#261
of 317 outputs
Outputs of similar age
#342,033
of 400,124 outputs
Outputs of similar age from Transfusion Clinique et Biologique
#4
of 5 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 317 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,124 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.