Title |
Glucose transporters: physiological and pathological roles
|
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Published in |
Biophysical Reviews, January 2016
|
DOI | 10.1007/s12551-015-0186-2 |
Pubmed ID | |
Authors |
Archana M. Navale, Archana N. Paranjape |
Abstract |
Glucose is a primary energy source for most cells and an important substrate for many biochemical reactions. As glucose is a need of each and every cell of the body, so are the glucose transporters. Consequently, all cells express these important proteins on their surface. In recent years developments in genetics have shed new light on the types and physiology of various glucose transporters, of which there are two main types-sodium-glucose linked transporters (SGLTs) and facilitated diffusion glucose transporters (GLUT)-which can be divided into many more subclasses. Transporters differ in terms of their substrate specificity, distribution and regulatory mechanisms. Glucose transporters have also received much attention as therapeutic targets for various diseases. In this review, we attempt to present a simplified view of this complex topic which may be of interest to researchers involved in biochemical and pharmacological research. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 775 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 127 | 16% |
Student > Ph. D. Student | 107 | 14% |
Student > Master | 103 | 13% |
Student > Doctoral Student | 41 | 5% |
Researcher | 40 | 5% |
Other | 77 | 10% |
Unknown | 280 | 36% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 157 | 20% |
Medicine and Dentistry | 73 | 9% |
Agricultural and Biological Sciences | 51 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 45 | 6% |
Neuroscience | 24 | 3% |
Other | 126 | 16% |
Unknown | 299 | 39% |