| Title |
How to Test and Treat Small Intestinal Bacterial Overgrowth: an Evidence-Based Approach
|
|---|---|
| Published in |
Current Gastroenterology Reports, January 2016
|
| DOI | 10.1007/s11894-015-0482-9 |
| Pubmed ID | |
| Authors |
Ali Rezaie, Mark Pimentel, Satish S. Rao |
| Abstract |
Small intestinal bacterial overgrowth (SIBO) is characterized by an excessive amount of bacteria in the small intestine and a constellation of symptoms that include bloating, pain, gas, and diarrhea. Although known for many decades, there is a lack of consensus and clarity regarding the natural history and methods for its diagnosis. Several tests have been proposed, including the glucose breath test, lactulose breath test, small intestinal aspiration and culture, and others. However, there is a lack of standardization of these tests and their interpretation. Treatment of SIBO remains empirical; generally, broad spectrum antibiotics are recommended for 2 weeks (amoxicillin, rifaximin, ciprofloxacin, etc.) but evidence for their use is fair. Clearly, there is a strong need to develop a systematic approach for the management of SIBO and to perform multicenter clinical trials for the treatment of SIBO. In this review, we will discuss the current evidence for the diagnosis and treatment of SIBO, which includes (1) elimination/modification of the underlying causes, (2) induction of remission (antibiotics and elemental diet), and (3) maintenance of remission (promotility drugs, dietary modifications, repeat or cyclical antibiotics). |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 44% |
| India | 1 | 4% |
| Belgium | 1 | 4% |
| Mexico | 1 | 4% |
| Canada | 1 | 4% |
| Saudi Arabia | 1 | 4% |
| United Kingdom | 1 | 4% |
| Unknown | 8 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 68% |
| Practitioners (doctors, other healthcare professionals) | 4 | 16% |
| Scientists | 4 | 16% |
Mendeley readers
The data shown below were compiled from readership statistics for 265 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 262 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 48 | 18% |
| Other | 32 | 12% |
| Researcher | 27 | 10% |
| Student > Master | 27 | 10% |
| Student > Postgraduate | 23 | 9% |
| Other | 45 | 17% |
| Unknown | 63 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 101 | 38% |
| Nursing and Health Professions | 37 | 14% |
| Agricultural and Biological Sciences | 17 | 6% |
| Biochemistry, Genetics and Molecular Biology | 7 | 3% |
| Engineering | 7 | 3% |
| Other | 28 | 11% |
| Unknown | 68 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 44. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 May 2023.
All research outputs
#941,908
of 25,457,858 outputs
Outputs from Current Gastroenterology Reports
#3
of 3 outputs
Outputs of similar age
#16,553
of 400,702 outputs
Outputs of similar age from Current Gastroenterology Reports
#1
of 4 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.9. This one scored the same or higher as 0 of them.
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