Title |
Antihyperlipidemic Effect of Syrian Mesquite (Prosopis farcta) Root in High Cholesterol Diet–Fed Rabbits
|
---|---|
Published in |
Journal of Evidence-Based Complementary & Alternative Medicine, June 2016
|
DOI | 10.1177/2156587215627552 |
Pubmed ID | |
Authors |
Mohammad Reza Saidi, Mohammad Hosein Farzaei, Shahram Miraghaee, Atefeh Babaei, Bahareh Mohammadi, Mohammad Taher Bahrami, Gholamreza Bahrami |
Abstract |
Prosopis farcta root has been proposed as an efficacious natural drug for cardiovascular disorders in traditional medicine. The present study evaluates the efficacy of aqueous extract of Prosopis farcta root on experimental atherosclerosis development in rabbits with high cholesterol diet-induced hypercholesterolemia. Serum lipid parameters were significantly increased in the high cholesterol diet groups in comparison with the normal control group (P < .050). Histopathological findings revealed that atheromatous plaques were formed in both thoracic and abdominal aorta of hypercholestrolemic rabbits. Treatment with Prosopis farcta root significantly reduced total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, and very low density lipoprotein levels compared to high cholesterol diet rabbits (P < .050). This finding may reflect a reduction of chest pain or the beneficial effects of this plant root extract on cardiovascular health. The present study can serve as a basis for future investigations on the other effects of this plant on cardiovascular health. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 4 | 19% |
Other | 2 | 10% |
Lecturer | 2 | 10% |
Student > Doctoral Student | 1 | 5% |
Unspecified | 1 | 5% |
Other | 4 | 19% |
Unknown | 7 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 14% |
Medicine and Dentistry | 3 | 14% |
Nursing and Health Professions | 3 | 14% |
Unspecified | 1 | 5% |
Environmental Science | 1 | 5% |
Other | 4 | 19% |
Unknown | 6 | 29% |