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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Progression of atrial remodeling in patients with high-burden atrial fibrillation: Implications for early ablative intervention
|
|---|---|
| Published in |
Heart Rhythm, October 2015
|
| DOI | 10.1016/j.hrthm.2015.10.028 |
| Pubmed ID | |
| Authors |
Tomos E. Walters, Ashley Nisbet, Gwilym M. Morris, Gabriel Tan, Megan Mearns, Eliza Teo, Nigel Lewis, AiVee Ng, Paul Gould, Geoffrey Lee, Stephen Joseph, Joseph B. Morton, Dominica Zentner, Prashanthan Sanders, Peter M. Kistler, Jonathan M. Kalman |
| Abstract |
Advanced atrial remodeling predicts poor clinical outcomes in human AF. We aimed to define the magnitude and predictors of change in LA structural remodeling over 12 months of AF. Thirty eight patients with paroxysmal AF managed medically (Group 1), 20 undergoing AF ablation (Group 2) and 25 control patients with no AF history (Group 3) prospectively underwent echocardiographic assessment of strain variables of LA reservoir function at baseline, 4, 8 and 12 months. In addition, P-wave duration (Pmax, , Pmean) and dispersion (Pdis) were measured. AF burden was quantified by implanted recorders. Twenty patients undergoing ablation underwent electroanatomic mapping (mean 333±40 points) for correlation with LA strain. Group 1 demonstrated significant deterioration in total LA strain (26.3±1.2% to 21.7±1.2%, P<0.05), and increases in Pmax (132±3ms to 138±3ms, P<0.05) and Pdis (37±2ms to 42±2ms, P<0.05). An AF burden ≥10% was specifically associated with decline in strain and with P-wave prolongation. Conversely, Group 2 manifest improvement in total LA strain (21.3±1.7% to 28.6±1.7%, P<0.05) and reductions in Pmax (136±4ms to 119±4ms, P<0.05) and Pdis (47±3ms to 32±3ms, P<0.05). Change was not significant in Group 3. LA mean voltage (r=0.71, P=0.0005), percent low voltage electrograms (r=-0.59, P=0.006), percent complex electrograms (r=-0.68, P=0.0009) and LA activation time (r=-0.69, P=0.001) correlated with total strain as a measure of LA reservoir function. High burden AF is associated with progressive LA structural remodeling. In contrast AF ablation results in significant reverse remodeling. These data may have implications for timing of ablative intervention. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 73 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 15% |
| Researcher | 9 | 12% |
| Other | 8 | 11% |
| Student > Master | 6 | 8% |
| Professor | 6 | 8% |
| Other | 17 | 23% |
| Unknown | 17 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 49% |
| Engineering | 6 | 8% |
| Nursing and Health Professions | 2 | 3% |
| Chemistry | 2 | 3% |
| Social Sciences | 1 | 1% |
| Other | 2 | 3% |
| Unknown | 25 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2016.
All research outputs
#17,343,547
of 25,450,869 outputs
Outputs from Heart Rhythm
#3,484
of 4,531 outputs
Outputs of similar age
#177,252
of 295,628 outputs
Outputs of similar age from Heart Rhythm
#32
of 42 outputs
Altmetric has tracked 25,450,869 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,531 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 295,628 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.