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Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer

Overview of attention for article published in Organic Letters, January 2016
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Title
Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer
Published in
Organic Letters, January 2016
DOI 10.1021/acs.orglett.5b03591
Pubmed ID
Authors

Anthony W. McDonagh, Mary F. Mahon, Paul V. Murphy

Abstract

The TiCl4 induced anomerization of selenium glycosides of galacturonic acid derivatives is reported. The reaction was successful for galacturonic acid when various alkyl, alkenyl, alkynyl, saccharide, steroid, and lipid groups were attached to the anomeric Se atom. An increased amount of TiCl4 and/or higher temperature were needed to ensure completion of the reaction in some cases. Yields were higher for reactions carried out at higher dilution. The reaction was applied to the synthesis of Se-based mimics of the potent immunostimulant α-GalCer (KRN7000).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 21%
Student > Bachelor 5 12%
Researcher 4 10%
Student > Doctoral Student 3 7%
Other 3 7%
Other 8 19%
Unknown 10 24%
Readers by discipline Count As %
Chemistry 25 60%
Unspecified 1 2%
Chemical Engineering 1 2%
Agricultural and Biological Sciences 1 2%
Engineering 1 2%
Other 0 0%
Unknown 13 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2016.
All research outputs
#14,705,554
of 22,840,638 outputs
Outputs from Organic Letters
#10,397
of 14,095 outputs
Outputs of similar age
#217,264
of 395,188 outputs
Outputs of similar age from Organic Letters
#58
of 161 outputs
Altmetric has tracked 22,840,638 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,095 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,188 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 161 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.