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Mendeley readers
Attention Score in Context
| Title |
Diffuse Optical Characterization of the Healthy Human Thyroid Tissue and Two Pathological Case Studies
|
|---|---|
| Published in |
PLOS ONE, January 2016
|
| DOI | 10.1371/journal.pone.0147851 |
| Pubmed ID | |
| Authors |
Claus Lindner, Mireia Mora, Parisa Farzam, Mattia Squarcia, Johannes Johansson, Udo M. Weigel, Irene Halperin, Felicia A. Hanzu, Turgut Durduran |
| Abstract |
The in vivo optical and hemodynamic properties of the healthy (n = 22) and pathological (n = 2) human thyroid tissue were measured non-invasively using a custom time-resolved spectroscopy (TRS) and diffuse correlation spectroscopy (DCS) system. Medical ultrasound was used to guide the placement of the hand-held hybrid optical probe. TRS measured the absorption and reduced scattering coefficients (μa, μs') at three wavelengths (690, 785 and 830 nm) to derive total hemoglobin concentration (THC) and oxygen saturation (StO2). DCS measured the microvascular blood flow index (BFI). Their dependencies on physiological and clinical parameters and positions along the thyroid were investigated and compared to the surrounding sternocleidomastoid muscle. The THC in the thyroid ranged from 131.9 μM to 144.8 μM, showing a 25-44% increase compared to the surrounding sternocleidomastoid muscle tissue. The blood flow was significantly higher in the thyroid (BFIthyroid = 16.0 × 10-9 cm2/s) compared to the muscle (BFImuscle = 7.8 × 10-9 cm2/s), while StO2 showed a small (StO2, muscle = 63.8% to StO2, thyroid = 68.4%), yet significant difference. Two case studies with thyroid nodules underwent the same measurement protocol prior to thyroidectomy. Their THC and BFI reached values around 226.5 μM and 62.8 × 10-9 cm2/s respectively showing a clear contrast to the nodule-free thyroid tissue as well as the general population. The initial characterization of the healthy and pathologic human thyroid tissue lays the ground work for the future investigation on the use of diffuse optics in thyroid cancer screening. |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Italy | 1 | 1% |
| Unknown | 70 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 29% |
| Researcher | 10 | 14% |
| Student > Master | 8 | 11% |
| Student > Doctoral Student | 5 | 7% |
| Professor > Associate Professor | 5 | 7% |
| Other | 10 | 14% |
| Unknown | 13 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 20 | 28% |
| Physics and Astronomy | 17 | 24% |
| Medicine and Dentistry | 6 | 8% |
| Agricultural and Biological Sciences | 3 | 4% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 6 | 8% |
| Unknown | 17 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2016.
All research outputs
#3,695,742
of 22,842,950 outputs
Outputs from PLOS ONE
#45,743
of 194,886 outputs
Outputs of similar age
#65,953
of 396,850 outputs
Outputs of similar age from PLOS ONE
#1,192
of 5,132 outputs
Altmetric has tracked 22,842,950 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 194,886 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,850 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 5,132 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.