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Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward

Overview of attention for article published in Expert Review of Clinical Immunology, March 2016
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Title
Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward
Published in
Expert Review of Clinical Immunology, March 2016
DOI 10.1586/1744666x.2016.1147955
Pubmed ID
Authors

Christina E. West, Maria C. Jenmalm, Anita L. Kozyrskyj, Susan L. Prescott

Abstract

Microbial ecosystems cover the surface of the human body and it is becoming increasingly clear that our modern environment has profound effects on microbial composition and diversity. A dysbiotic gut microbiota has been associated with allergic diseases and asthma in cross-sectional and observational studies. In an attempt to restore this dysbiosis, probiotics have been evaluated in randomized controlled trials. Here, we review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context. Many meta-analyses have shown a moderate benefit of probiotics for eczema prevention, whereas there is less evidence of a benefit for other allergic manifestations. Because of very low quality evidence and heterogeneity between studies, specific advice on the most effective regimens cannot yet be given - not even for eczema prevention. To be able to adopt results into specific recommendations, international expert organizations stress the need for well-designed studies.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 120 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 23 19%
Researcher 16 13%
Student > Ph. D. Student 15 13%
Student > Master 13 11%
Other 8 7%
Other 20 17%
Unknown 25 21%
Readers by discipline Count As %
Medicine and Dentistry 30 25%
Agricultural and Biological Sciences 18 15%
Immunology and Microbiology 12 10%
Biochemistry, Genetics and Molecular Biology 11 9%
Nursing and Health Professions 8 7%
Other 15 13%
Unknown 26 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2017.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from Expert Review of Clinical Immunology
#534
of 968 outputs
Outputs of similar age
#180,151
of 313,453 outputs
Outputs of similar age from Expert Review of Clinical Immunology
#14
of 29 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 968 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,453 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.