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Therapeutically targeting SELF‐reinforcing leukemic niches in acute myeloid leukemia: A worthy endeavor?

Overview of attention for article published in American Journal of Hematology, April 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

Mentioned by

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6 X users

Citations

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20 Dimensions

Readers on

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42 Mendeley
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Title
Therapeutically targeting SELF‐reinforcing leukemic niches in acute myeloid leukemia: A worthy endeavor?
Published in
American Journal of Hematology, April 2016
DOI 10.1002/ajh.24312
Pubmed ID
Authors

Paolo Bernasconi, Mirko Farina, Marina Boni, Irene Dambruoso, Celeste Calvello

Abstract

A tight relationship between the Acute Myeloid Leukemia (AML) population and the bone marrow (BM) microenvironment has been convincingly established. The AML clone contains leukemic stem cells (LSCs) that compete with normal hematopoietic stem cells (HSCs) for niche occupancy and remodel the niche; whereas, the BM microenvironment might promote AML development and progression not only through hypoxia and homing/adhesion molecules, but also through genetic defects. Although it is still unknown whether the niche influences treatment results or contains any potential target for treatment, this dynamic AML-niche interaction might be a promising therapeutic objective to significantly improve the AML cure rate. This article is protected by copyright. All rights reserved.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 17%
Student > Ph. D. Student 6 14%
Researcher 5 12%
Student > Postgraduate 3 7%
Professor > Associate Professor 3 7%
Other 8 19%
Unknown 10 24%
Readers by discipline Count As %
Medicine and Dentistry 9 21%
Biochemistry, Genetics and Molecular Biology 6 14%
Agricultural and Biological Sciences 5 12%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Engineering 2 5%
Other 5 12%
Unknown 12 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2016.
All research outputs
#13,973,827
of 24,477,448 outputs
Outputs from American Journal of Hematology
#2,136
of 3,570 outputs
Outputs of similar age
#142,432
of 305,452 outputs
Outputs of similar age from American Journal of Hematology
#29
of 72 outputs
Altmetric has tracked 24,477,448 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,570 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,452 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.