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‘Pre-prosthetic use of poly(lactic-co-glycolic acid) membranes treated with oxygen plasma and TiO2 nanocomposite particles for guided bone regeneration processes’

Overview of attention for article published in Journal of Dental Medicine, February 2016
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Title
‘Pre-prosthetic use of poly(lactic-co-glycolic acid) membranes treated with oxygen plasma and TiO2 nanocomposite particles for guided bone regeneration processes’
Published in
Journal of Dental Medicine, February 2016
DOI 10.1016/j.jdent.2016.01.015
Pubmed ID
Authors

Gabriel Castillo-Dalí, Raquel Castillo-Oyagüe, Antonia Terriza, Jean-Louis Saffar, Antonio Batista-Cruzado, Christopher D. Lynch, Alastair J. Sloan, José-Luis Gutiérrez-Pérez, Daniel Torres-Lagares

Abstract

Guided bone regeneration (GBR) processes are frequently necessary to achieve appropriate substrates before the restoration of edentulous areas. This study aimed to evaluate the bone regeneration reliability of a new poly-lactic-co-glycolic acid (PLGA) membrane after treatment with oxygen plasma (PO2) and titanium dioxide (TiO2) composite nanoparticles. Circumferential bone defects (diameter: 10 mm; depth: 3 mm) were created on the parietal bones of eight experimentation rabbits and were randomly covered with control membranes (Group 1: PLGA) or experimental membranes (Group 2: PLGA/PO2/TiO2). The animals were euthanized two months afterwards, and a morphologic study was then performed under microscope using ROI (region of interest) colour analysis. Percentage of new bone formation, length of mineralised bone formed in the grown defects, concentration of osteoclasts, and intensity of osteosynthetic activity were assessed. Comparisons among the groups and with the original bone tissue were made using the Kruskal-Wallis test. The level of significance was set in advance at a = 0.05. The experimental group recorded higher values for new bone formation, mineralised bone length, and osteoclast concentration; this group also registered the highest osteosynthetic activity. Bone layers in advanced formation stages and low proportions of immature tissue were observed in the study group. The functionalised membranes showed the best efficacy for bone regeneration. The addition of TiO2 nanoparticles onto PLGA/PO2 membranes for GBR processes may be a promising technique to restore bone dimensions and anatomic contours as a prerequisite to well-supported and natural-appearing prosthetic rehabilitations.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 45 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 29%
Student > Postgraduate 4 9%
Student > Doctoral Student 4 9%
Professor 3 7%
Other 3 7%
Other 9 20%
Unknown 9 20%
Readers by discipline Count As %
Medicine and Dentistry 13 29%
Materials Science 4 9%
Engineering 4 9%
Agricultural and Biological Sciences 3 7%
Immunology and Microbiology 2 4%
Other 7 16%
Unknown 12 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2016.
All research outputs
#17,351,840
of 25,460,914 outputs
Outputs from Journal of Dental Medicine
#971
of 1,516 outputs
Outputs of similar age
#247,349
of 406,404 outputs
Outputs of similar age from Journal of Dental Medicine
#10
of 19 outputs
Altmetric has tracked 25,460,914 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,516 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 406,404 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.