| Title |
Risk factors for Barrett’s esophagus: a scoping review
|
|---|---|
| Published in |
Cancer Causes & Control, February 2016
|
| DOI | 10.1007/s10552-015-0710-5 |
| Pubmed ID | |
| Authors |
Colin J. Ireland, Sarah K. Thompson, Thomas A. Laws, Adrian Esterman |
| Abstract |
Cancer of the esophagus is a highly lethal disease with many patients presenting with metastatic spread of their tumor at diagnosis; a consequence of this late presentation is the 5-year survival rate of <20 %. Barrett's esophagus (BE), a premalignant condition of the distal esophagus, is the main risk factor for adenocarcinoma of the esophagus. The development of a risk prediction tool that could assist healthcare professionals in identifying people at increased risk of developing BE would be advantageous. Understanding the factors that influence the risk of developing BE is the first stage of developing a risk prediction tool. A scoping review was undertaken to address the following question 'what factors influence the risk of developing Barrett's esophagus?' Forty-six articles were included in this review. The majority of articles reviewed were case-control or cohort studies. Samples sizes ranged from 68 to 84,606. Risk factors reported to be statistically significant were divided into three categories: demographic, lifestyle and clinical factors. Strongest risk factors identified include: male gender, increasing age, white race, smoking, obesity and gastro-esophageal reflux disease symptoms, while some aspects of a person's diet appear to act as a protective measure. Risk factors for BE are complex and need to be considered by healthcare professionals when identifying patients that could benefit from endoscopic eradication. These results provide a stepping stone for the future development of a risk prediction model. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 8 | 15% |
| Student > Ph. D. Student | 8 | 15% |
| Student > Bachelor | 7 | 13% |
| Researcher | 5 | 9% |
| Student > Doctoral Student | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 14 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 32% |
| Agricultural and Biological Sciences | 4 | 8% |
| Economics, Econometrics and Finance | 4 | 8% |
| Nursing and Health Professions | 3 | 6% |
| Psychology | 3 | 6% |
| Other | 4 | 8% |
| Unknown | 18 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2016.
All research outputs
#16,171,492
of 23,854,458 outputs
Outputs from Cancer Causes & Control
#1,632
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Outputs of similar age
#240,651
of 403,499 outputs
Outputs of similar age from Cancer Causes & Control
#14
of 21 outputs
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