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Mendeley readers
Attention Score in Context
| Title |
A Genetic Defect Caused by a Triplet Repeat Expansion in Arabidopsis thaliana
|
|---|---|
| Published in |
Science, January 2009
|
| DOI | 10.1126/science.1164014 |
| Pubmed ID | |
| Authors |
Sridevi Sureshkumar, Marco Todesco, Korbinian Schneeberger, Ramya Harilal, Sureshkumar Balasubramanian, Detlef Weigel |
| Abstract |
Variation in the length of simple DNA triplet repeats has been linked to phenotypic variability in microbes and to several human disorders. Population-level forces driving triplet repeat contraction and expansion in multicellular organisms are, however, not well understood. We have identified a triplet repeat-associated genetic defect in an Arabidopsis thaliana variety collected from the wild. The Bur-0 strain carries a dramatically expanded TTC/GAA repeat in the intron of the ISOPROPYL MALATE ISOMERASE LARGE SUB UNIT1 (IIL1; At4g13430) gene. The repeat expansion causes an environment-dependent reduction in IIL1 activity and severely impairs growth of this strain, whereas contraction of the expanded repeat can reverse the detrimental phenotype. The Bur-0 IIL1 defect thus presents a genetically tractable model for triplet repeat expansions and their variability in natural populations. |
Mendeley readers
The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 3 | 2% |
| Germany | 2 | 2% |
| United Kingdom | 2 | 2% |
| Norway | 2 | 2% |
| Austria | 1 | <1% |
| Sweden | 1 | <1% |
| France | 1 | <1% |
| Israel | 1 | <1% |
| Canada | 1 | <1% |
| Other | 2 | 2% |
| Unknown | 107 | 87% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 45 | 37% |
| Student > Ph. D. Student | 20 | 16% |
| Student > Master | 11 | 9% |
| Professor | 10 | 8% |
| Student > Doctoral Student | 7 | 6% |
| Other | 19 | 15% |
| Unknown | 11 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 80 | 65% |
| Biochemistry, Genetics and Molecular Biology | 19 | 15% |
| Computer Science | 4 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Medicine and Dentistry | 2 | 2% |
| Other | 4 | 3% |
| Unknown | 12 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2009.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Science
#71,518
of 82,915 outputs
Outputs of similar age
#165,070
of 194,328 outputs
Outputs of similar age from Science
#341
of 366 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 82,915 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 65.7. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,328 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 366 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.