| Title |
Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border
|
|---|---|
| Published in |
Malaria Journal, November 2010
|
| DOI | 10.1186/1475-2875-9-308 |
| Pubmed ID | |
| Authors |
Rie Takeuchi, Saranath Lawpoolsri, Mallika Imwong, Jun Kobayashi, Jaranit Kaewkungwal, Sasithon Pukrittayakamee, Supalap Puangsa-art, Nipon Thanyavanich, Wanchai Maneeboonyang, Nicholas PJ Day, Pratap Singhasivanon |
| Abstract |
Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug and adherence to the 14-day regimen. This study examined the effectiveness of using the directly-observed therapy (DOT) method for the radical treatment of P. vivax malaria infection, to prevent reappearance of the parasite within the 90-day follow-up period. Other potential risk factors for the reappearance of P. vivax were also explored. |
Mendeley readers
The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 2% |
| Australia | 1 | <1% |
| Pakistan | 1 | <1% |
| South Africa | 1 | <1% |
| Philippines | 1 | <1% |
| Unknown | 111 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 15% |
| Student > Ph. D. Student | 15 | 13% |
| Student > Master | 15 | 13% |
| Other | 10 | 9% |
| Student > Bachelor | 8 | 7% |
| Other | 24 | 21% |
| Unknown | 28 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 38 | 32% |
| Agricultural and Biological Sciences | 18 | 15% |
| Biochemistry, Genetics and Molecular Biology | 6 | 5% |
| Social Sciences | 6 | 5% |
| Nursing and Health Professions | 4 | 3% |
| Other | 16 | 14% |
| Unknown | 29 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2016.
All research outputs
#6,377,613
of 22,660,862 outputs
Outputs from Malaria Journal
#1,849
of 5,538 outputs
Outputs of similar age
#31,395
of 100,154 outputs
Outputs of similar age from Malaria Journal
#8
of 44 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 5,538 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 100,154 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.