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Mendeley readers
Attention Score in Context
| Title |
Common variants at ten loci modulate the QT interval duration in the QTSCD Study
|
|---|---|
| Published in |
Nature Genetics, March 2009
|
| DOI | 10.1038/ng.362 |
| Pubmed ID | |
| Authors |
Arne Pfeufer, Serena Sanna, Dan E Arking, Martina Müller, Vesela Gateva, Christian Fuchsberger, Georg B Ehret, Marco Orrú, Cristian Pattaro, Anna Köttgen, Siegfried Perz, Gianluca Usala, Maja Barbalic, Man Li, Benno Pütz, Angelo Scuteri, Ronald J Prineas, Moritz F Sinner, Christian Gieger, Samer S Najjar, W H Linda Kao, Thomas W. Mühleisen, Mariano Dei, Christine Happle, Stefan Möhlenkamp, Laura Crisponi, Raimund Erbel, Karl-Heinz Jöckel, Silvia Naitza, Gerhard Steinbeck, Fabio Marroni, Andrew A Hicks, Edward Lakatta, Bertram Müller-Myhsok, Peter P Pramstaller, H-Erich Wichmann, David Schlessinger, Eric Boerwinkle, Thomas Meitinger, Manuela Uda, Josef Coresh, Stefan Kääb, Gonçalo R Abecasis, Aravinda Chakravarti |
| Abstract |
The QT interval, a measure of cardiac repolarization, predisposes to ventricular arrhythmias and sudden cardiac death (SCD) when prolonged or shortened. A common variant in NOS1AP is known to influence repolarization. We analyze genome-wide data from five population-based cohorts (ARIC, KORA, SardiNIA, GenNOVA and HNR) with a total of 15,842 individuals of European ancestry, to confirm the NOS1AP association and identify nine additional loci at P < 5 x 10(-8). Four loci map near the monogenic long-QT syndrome genes KCNQ1, KCNH2, SCN5A and KCNJ2. Two other loci include ATP1B1 and PLN, genes with established electrophysiological function, whereas three map to RNF207, near LITAF and within NDRG4-GINS3-SETD6-CNOT1, respectively, all of which have not previously been implicated in cardiac electrophysiology. These results, together with an accompanying paper from the QTGEN consortium, identify new candidate genes for ventricular arrhythmias and SCD. |
Mendeley readers
The data shown below were compiled from readership statistics for 195 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | 2% |
| Switzerland | 2 | 1% |
| United Kingdom | 2 | 1% |
| Italy | 1 | <1% |
| Netherlands | 1 | <1% |
| Canada | 1 | <1% |
| New Zealand | 1 | <1% |
| Denmark | 1 | <1% |
| Spain | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 181 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 52 | 27% |
| Student > Ph. D. Student | 39 | 20% |
| Other | 17 | 9% |
| Professor | 16 | 8% |
| Student > Master | 11 | 6% |
| Other | 36 | 18% |
| Unknown | 24 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 58 | 30% |
| Medicine and Dentistry | 55 | 28% |
| Biochemistry, Genetics and Molecular Biology | 32 | 16% |
| Computer Science | 3 | 2% |
| Earth and Planetary Sciences | 2 | 1% |
| Other | 14 | 7% |
| Unknown | 31 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2016.
All research outputs
#2,264,891
of 22,660,862 outputs
Outputs from Nature Genetics
#2,791
of 7,173 outputs
Outputs of similar age
#7,236
of 93,456 outputs
Outputs of similar age from Nature Genetics
#28
of 60 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,173 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 40.9. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 93,456 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.