| Title |
Effect of elevated blood pressure on quality of life in children with chronic kidney disease
|
|---|---|
| Published in |
Pediatric Nephrology, February 2016
|
| DOI | 10.1007/s00467-015-3262-8 |
| Pubmed ID | |
| Authors |
Cynthia Wong, Arlene Gerson, Stephen R. Hooper, Matthew Matheson, Marc Lande, Juan Kupferman, Susan Furth, Bradley Warady, Joseph Flynn, For the Chronic Kidney Disease in Children (CKiD) Study |
| Abstract |
Although hypertension is known to have an adverse impact on health-related quality of life (HRQoL) in adults, little is known about the effects of hypertension and use of antihypertensive medications on HRQoL in hypertensive children with chronic kidney disease (CKD). Cross-sectional and longitudinal assessment of impact of elevated blood pressure (BP) and antihypertensive medication use on HRQoL scores obtained in children enrolled in the Chronic Kidney Disease in Children (CKiD) Study. Blood pressure was measured both manually and by ambulatory blood pressure monitoring. HRQoL was assessed with the PedsQL survey. The study sample included 551 participants with sufficient data for cross-sectional and longitudinal analyses. Cross-sectional analysis of presence of prehypertension or hypertension and impact on HRQoL found mild associations between elevated BP and HRQoL scores with overall PedsQL parent and child scores averaging 79 vs. 76.5 and 83 vs. 78.5, respectively. However, no associations persisted under longitudinal multivariate analysis. Despite apparent small effects of elevated BP on HRQoL at baseline, no association was found between the presence of elevated BP and HRQoL over time in children with mild-to-moderate CKD. In addition, antihypertensive medication use did not appear to have an impact on HRQoL in this population. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 2 | 50% |
| Members of the public | 2 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Slovenia | 1 | 2% |
| Unknown | 41 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 7 | 17% |
| Other | 4 | 10% |
| Student > Bachelor | 4 | 10% |
| Professor | 4 | 10% |
| Researcher | 2 | 5% |
| Other | 4 | 10% |
| Unknown | 17 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 31% |
| Nursing and Health Professions | 4 | 10% |
| Psychology | 2 | 5% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Economics, Econometrics and Finance | 1 | 2% |
| Other | 2 | 5% |
| Unknown | 19 | 45% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2016.
All research outputs
#14,247,377
of 22,844,985 outputs
Outputs from Pediatric Nephrology
#2,423
of 3,544 outputs
Outputs of similar age
#209,756
of 398,933 outputs
Outputs of similar age from Pediatric Nephrology
#30
of 67 outputs
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