| Title |
Elevation of homocysteine levels is only partially reversed after therapy in females with eating disorders
|
|---|---|
| Published in |
Journal of Neural Transmission, February 2010
|
| DOI | 10.1007/s00702-010-0379-6 |
| Pubmed ID | |
| Authors |
Julia Wilhelm, Elisabeth Müller, Martina de Zwaan, Julia Fischer, Thomas Hillemacher, Johannes Kornhuber, Stefan Bleich, Helge Frieling |
| Abstract |
Recent studies have shown elevated homocysteine levels in patients with eating disorders. In a prospective, longitudinal study, we investigated differences of homocysteine plasma levels in patients with anorexia nervosa (N = 12) and bulimia nervosa (N = 17) compared to healthy controls (N = 20) and alteration of homocysteine levels in patients during specific in-patient treatment. We found significantly elevated homocysteine levels in both patient groups (anorexia nervosa and bulimia nervosa) and a non-significant decrease of homocysteine during the 12-week treatment period. Furthermore, we found a significant association between low homocysteine levels and cognitive deficits, pointing toward a beneficial effect of elevated homocysteine levels on cognition in this patient group. We suppose that during effective treatment with significant increase of the body mass index, the observed hyperhomocysteinemia in patients with eating disorders is partially reversible. These findings add further evidence to the hypothesis that homocysteine might be involved in the pathophysiology of anorexia and bulimia nervosa. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 5% |
| Unknown | 42 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 9 | 20% |
| Student > Master | 9 | 20% |
| Researcher | 7 | 16% |
| Student > Postgraduate | 3 | 7% |
| Student > Ph. D. Student | 3 | 7% |
| Other | 5 | 11% |
| Unknown | 8 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 11 | 25% |
| Medicine and Dentistry | 9 | 20% |
| Agricultural and Biological Sciences | 3 | 7% |
| Nursing and Health Professions | 3 | 7% |
| Mathematics | 1 | 2% |
| Other | 5 | 11% |
| Unknown | 12 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2016.
All research outputs
#14,723,579
of 22,660,862 outputs
Outputs from Journal of Neural Transmission
#1,199
of 1,760 outputs
Outputs of similar age
#75,851
of 93,438 outputs
Outputs of similar age from Journal of Neural Transmission
#4
of 4 outputs
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