Title |
Geographic differences in the target-controlled infusion estimated concentration of propofol: bispectral index response curves
|
---|---|
Published in |
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, January 2011
|
DOI | 10.1007/s12630-011-9453-2 |
Pubmed ID | |
Authors |
Ashraf A. Dahaba, Taidi Zhong, Hui Shun Lu, Helmar Bornemann, Markus Liebmann, Georg Wilfinger, Gilbert Reibnegger, Helfried Metzler |
Abstract |
Variability in drug responses could result from both genetic and environmental factors. Thus, drug effect could depend on geographic location, although regional variation is not generally acknowledged as a basis for stratification. There is evidence that the pharmacokinetic set developed in a European population for the target-controlled infusion (TCI) of propofol does not apply in Chinese patients; however, we are not aware of previous studies comparing the estimated concentration-bispectral index (BIS) response of Caucasian patients in Europe with that of Chinese patients in China. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Austria | 1 | 5% |
Unknown | 20 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 29% |
Student > Ph. D. Student | 4 | 19% |
Other | 1 | 5% |
Professor | 1 | 5% |
Student > Doctoral Student | 1 | 5% |
Other | 2 | 10% |
Unknown | 6 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 57% |
Philosophy | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Unknown | 6 | 29% |