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Systems Chemical Biology

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Cover of 'Systems Chemical Biology'

Table of Contents

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    Book Overview
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    Chapter 1 PREDECT Protocols for Complex 2D/3D Cultures
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    Chapter 2 Phenotypic Screening Using Mouse and Human Stem Cell-Based Models of Neuroinflammation and Gene Expression Analysis to Study Drug Responses
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    Chapter 3 Quantitative, Real-Time Measurements of Intracellular Target Engagement Using Energy Transfer
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    Chapter 4 Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels
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    Chapter 5 Visualizing Bioactive Small Molecules by Alkyne Tagging and Slit-Scanning Raman Microscopy
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    Chapter 6 The Cell Painting Assay as a Screening Tool for the Discovery of Bioactivities in New Chemical Matter
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    Chapter 7 Proteomic Profiling for Target Identification of Biologically Active Small Molecules Using 2D DIGE
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    Chapter 8 Examining Cellular Responses to Kinase Drug Inhibition Through Phosphoproteome Mapping of Substrates
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    Chapter 9 CRISPR/Cas9-Based Chemogenomic Profiling in Mammalian Cells
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    Chapter 10 Exome Sequencing of Drug-Resistant Clones for Target Identification
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    Chapter 11 The Use of Large-Scale Chemically-Induced Transcriptome Data Acquired from LINCS to Study Small Molecules
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    Chapter 12 Integrated Analysis of Drug Sensitivity and Selectivity to Predict Synergistic Drug Combinations and Target Coaddictions in Cancer
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    Chapter 13 Predicting Drug Interactions From Chemogenomics Using INDIGO
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    Chapter 14 Computational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell Lines
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    Chapter 15 Web-Based Tools for Polypharmacology Prediction
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    Chapter 16 In Silico Target Prediction for Small Molecules
Attention for Chapter 9: CRISPR/Cas9-Based Chemogenomic Profiling in Mammalian Cells
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Chapter title
CRISPR/Cas9-Based Chemogenomic Profiling in Mammalian Cells
Chapter number 9
Book title
Systems Chemical Biology
Published by
Humana Press, New York, NY, January 2019
DOI 10.1007/978-1-4939-8891-4_9
Pubmed ID
Book ISBNs
978-1-4939-8890-7, 978-1-4939-8891-4
Authors

Dominic Hoepfner, Gregory McAllister, Gregory R. Hoffman, Hoepfner, Dominic, McAllister, Gregory, Hoffman, Gregory R.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 1 11%
Other 1 11%
Student > Bachelor 1 11%
Student > Ph. D. Student 1 11%
Student > Master 1 11%
Other 2 22%
Unknown 2 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 2 22%
Biochemistry, Genetics and Molecular Biology 2 22%
Philosophy 1 11%
Unspecified 1 11%
Chemistry 1 11%
Other 1 11%
Unknown 1 11%