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An update and systematic review on the treatment of primary dysmenorrhea

Overview of attention for article published in JBRA Assisted Reproduction, January 2019
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Title
An update and systematic review on the treatment of primary dysmenorrhea
Published in
JBRA Assisted Reproduction, January 2019
DOI 10.5935/1518-0557.20180083
Pubmed ID
Authors

Maedeh Sharghi, Shabnam Malekpour Mansurkhani, Damoon Ashtary Larky, Wesam Kooti, Mehdi Niksefat, Mohammad Firoozbakht, Masoud Behzadifar, Milad Azami, Karo Servatyari, Leila Jouybari

Abstract

Primary dysmenorrhea is a painful uterine contraction caused by endometrial laceration. Drug therapies and complementary medicine have been used to treat dysmenorrhea. The aim of this study was to investigate and offer an updated perspective on the treatments for dysmenorrhea. The present study was conducted in accordance with the PRISMA checklist for systematic reviews and meta-analyses. The required information was collected based on searches for the following keywords: treatment, primary dysmenorrhea, medicinal plants, chemical drugs, and herbs. Searches were performed on databases Pubmed, Web of Sciences, Scopus, Iran medex, and SID by March 2018 to find literature in the English and Persian languages on this subject without a time limit. This review included 17 papers, 10 of which on complementary medicine, three on drug therapies, and four on acupuncture and acupressure. The largest and smallest samples had 303 and 24 patients, respectively. Length of treatment ranged from one to six months and the measures most commonly used in the studies were the visual analogue scale and clinical efficacy. Reported complications included gastrointestinal events, nausea, vomiting, diarrhea, abdominal pain, and liver and kidney disorders. Medicinal plants, drugs, and acupressure seem to suppress pain by reducing the level of prostaglandins, mediating nitric oxide, increasing beta-endorphin levels, blocking the calcium channel, and enhancing circulatory flow through the uterine pathway. Further trials are required to confirm the benefits of the procedures described and ensure the absence of complications.

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Geographical breakdown

Country Count As %
Unknown 361 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 52 14%
Student > Master 30 8%
Lecturer 16 4%
Other 13 4%
Student > Doctoral Student 12 3%
Other 42 12%
Unknown 196 54%
Readers by discipline Count As %
Nursing and Health Professions 68 19%
Medicine and Dentistry 50 14%
Pharmacology, Toxicology and Pharmaceutical Science 11 3%
Biochemistry, Genetics and Molecular Biology 6 2%
Unspecified 5 1%
Other 20 6%
Unknown 201 56%