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BCL-2 Family Proteins

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Cover of 'BCL-2 Family Proteins'

Table of Contents

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    Book Overview
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    Chapter 1 Overview of BCL-2 Family Proteins and Therapeutic Potentials
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    Chapter 2 Database and Bioinformatic Analysis of BCL-2 Family Proteins and BH3-Only Proteins
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    Chapter 3 Application of Mito-Priming to Generate BCL-2 Addicted Cells
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    Chapter 4 BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies
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    Chapter 5 Flow Cytometry-Based Detection and Analysis of BCL-2 Family Proteins and Mitochondrial Outer Membrane Permeabilization (MOMP)
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    Chapter 6 Investigating BCL-2 Family Protein Interactions in Yeast
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    Chapter 7 Liposomal Permeabilization Assay to Study the Functional Interactions of the BCL-2 Family
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    Chapter 8 Mitochondrial Isolation and Real-Time Monitoring of MOMP
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    Chapter 9 Photocrosslinking Approach to Investigate Protein Interactions in the BCL-2 Family
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    Chapter 10 Assessment of Dynamic BCL-2 Protein Shuttling Between Outer Mitochondrial Membrane and Cytosol
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    Chapter 11 Quantification of BCL-2 Family Members by Flow Cytometry
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    Chapter 12 Methods to Probe Calcium Regulation by BCL-2 Family Members
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    Chapter 13 Methods to Probe Conformational Activation and Mitochondrial Activity of Proapoptotic BAK
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    Chapter 14 Probing BAK and BAX Activation and Pore Assembly with Cytochrome c Release, Limited Proteolysis, and Oxidant-Induced Linkage
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    Chapter 15 BCL-2 Protein Family Interaction Analysis by Nuclear Magnetic Resonance Spectroscopy
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    Chapter 16 Reconstitution and Characterization of BCL-2 Family Proteins in Lipid Bilayer Nanodiscs
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    Chapter 17 Cryo-Electron Microscopy to Study Bax Pores and MOMP
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    Chapter 18 CW EPR and DEER Methods to Determine BCL-2 Family Protein Structure and Interactions: Application of Site-Directed Spin Labeling to BAK Apoptotic Pores
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    Chapter 19 Rapid Imaging of BCL-2 Family Interactions in Live Cells Using FLIM-FRET
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    Chapter 20 Quantification of the Interactions Between BCL-2 Proteins by Fluorescence Correlation Spectroscopy
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    Chapter 21 Isolation of Synthetic Antibodies Against BCL-2-Associated X Protein (BAX)
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Title
BCL-2 Family Proteins
Published by
Springer New York, January 2019
DOI 10.1007/978-1-4939-8861-7
ISBNs
978-1-4939-8860-0, 978-1-4939-8861-7
Editors

Evripidis Gavathiotis

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