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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury*
|
|---|---|
| Published in |
Critical Care Medicine, July 2008
|
| DOI | 10.1097/ccm.0b013e31817d1b59 |
| Pubmed ID | |
| Authors |
Donall F. O’Croinin, Alistair D. Nichol, Natalie Hopkins, John Boylan, Sorca O’Brien, Clare O’Connor, John G. Laffey, Paul McLoughlin |
| Abstract |
Hypercapnic acidosis is commonly permitted in patients with acute respiratory distress syndrome during the use of protective ventilation strategies. Hypercapnic acidosis is also a common complication of multiple lung diseases and is associated with a poor prognosis, although the mechanisms by which it leads to increased mortality is not known. Previous studies using noninfective models of lung injury show that acute (<6 hrs) hypercapnic acidosis reduced lung damage by an anti-inflammatory effect. We hypothesized that this anti-inflammatory effect would be detrimental in vivo in the presence of untreated bacterial infection and sustained hypercapnia (>48 hrs) and, furthermore, that if bacterial reproduction were controlled by antibiotic therapy, then the anti-inflammatory effects of hypercapnic acidosis would no longer prove detrimental. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Switzerland | 1 | 2% |
| Canada | 1 | 2% |
| Unknown | 63 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 15% |
| Other | 9 | 14% |
| Researcher | 8 | 12% |
| Student > Bachelor | 7 | 11% |
| Student > Postgraduate | 6 | 9% |
| Other | 16 | 24% |
| Unknown | 10 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 55% |
| Agricultural and Biological Sciences | 6 | 9% |
| Biochemistry, Genetics and Molecular Biology | 4 | 6% |
| Arts and Humanities | 3 | 5% |
| Psychology | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 10 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2021.
All research outputs
#14,600,874
of 25,374,917 outputs
Outputs from Critical Care Medicine
#6,542
of 9,342 outputs
Outputs of similar age
#79,190
of 95,611 outputs
Outputs of similar age from Critical Care Medicine
#42
of 52 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,342 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,611 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.