| Title |
The nuclear factor-κB inhibitor pyrrolidine dithiocarbamate reduces polyinosinic-polycytidilic acid-induced immune response in pregnant rats and the behavioral defects of their adult offspring
|
|---|---|
| Published in |
Behavioral and Brain Functions, December 2011
|
| DOI | 10.1186/1744-9081-7-50 |
| Pubmed ID | |
| Authors |
Xueqin Song, Wenqiang Li, Yongfeng Yang, Jingping Zhao, Chengdi Jiang, Wei Li, Luxian Lv |
| Abstract |
Epidemiological studies have indicated that maternal infection during pregnancy may lead to a higher incidence of schizophrenia in the offspring. It is assumed that the maternal infection increases the immune response, leading to neurodevelopmental disorders in the offspring. Maternal polyinosinic-polycytidilic acid (PolyI:C) treatment induces a wide range of characteristics in the offspring mimicking some schizophrenia symptoms in humans. These observations are consistent with the neurodevelopmental hypothesis of schizophrenia. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 59 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 18% |
| Student > Master | 8 | 13% |
| Student > Bachelor | 7 | 12% |
| Researcher | 5 | 8% |
| Student > Doctoral Student | 4 | 7% |
| Other | 12 | 20% |
| Unknown | 13 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 11 | 18% |
| Medicine and Dentistry | 9 | 15% |
| Agricultural and Biological Sciences | 8 | 13% |
| Neuroscience | 6 | 10% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Other | 7 | 12% |
| Unknown | 15 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2011.
All research outputs
#15,240,835
of 22,660,862 outputs
Outputs from Behavioral and Brain Functions
#241
of 389 outputs
Outputs of similar age
#162,735
of 243,367 outputs
Outputs of similar age from Behavioral and Brain Functions
#13
of 20 outputs
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