| Title |
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
|
|---|---|
| Published in |
Diabetologia, July 2007
|
| DOI | 10.1007/s00125-007-0753-6 |
| Pubmed ID | |
| Authors |
S. A. Schäfer, O. Tschritter, F. Machicao, C. Thamer, N. Stefan, B. Gallwitz, J. J. Holst, J. M. Dekker, L. M. t’Hart, G. Nijpels, T. W. van Haeften, H. U. Häring, A. Fritsche |
| Abstract |
Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes and reduced insulin secretion. The transcription factor TCF7L2 is an essential factor for glucagon-like peptide-1 (GLP-1) secretion from intestinal L cells. We studied whether a defect in the enteroinsular axis contributes to impaired insulin secretion in carriers of TCF7L2 polymorphisms. |
Mendeley readers
The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | <1% |
| India | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 109 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 17% |
| Researcher | 19 | 17% |
| Student > Master | 16 | 14% |
| Student > Bachelor | 13 | 12% |
| Professor > Associate Professor | 6 | 5% |
| Other | 23 | 21% |
| Unknown | 16 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 25% |
| Biochemistry, Genetics and Molecular Biology | 26 | 23% |
| Medicine and Dentistry | 21 | 19% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Computer Science | 2 | 2% |
| Other | 11 | 10% |
| Unknown | 18 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2019.
All research outputs
#6,377,613
of 22,660,862 outputs
Outputs from Diabetologia
#2,565
of 5,023 outputs
Outputs of similar age
#21,545
of 67,039 outputs
Outputs of similar age from Diabetologia
#12
of 33 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 5,023 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 67,039 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.