Title |
Dual-energy CT of the heart for diagnosing coronary artery stenosis and myocardial ischemia-initial experience
|
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Published in |
European Radiology, June 2008
|
DOI | 10.1007/s00330-008-1022-x |
Pubmed ID | |
Authors |
Balazs Ruzsics, Heon Lee, Peter L. Zwerner, Mulugeta Gebregziabher, Philip Costello, U. Joseph Schoepf |
Abstract |
We aimed to evaluate the feasibility of diagnosing coronary stenosis and myocardial ischemia with a single dual-energy CT (DECT) acquisition. Thirty-five patients underwent contrast-enhanced, ECG-gated DECT of the heart while independently operating the two tubes of a dual-source CT system at high- and low-energy X-ray spectra. From the same raw data, coronary CTA (cCTA) studies were reconstructed for stenosis detection, and the myocardial blood-pool was analyzed by determining the tissue iodine content. Two independent observers analyzed all studies for stenosis and myocardial blood-pool deficits. Results were correlated with SPECT, coronary catheterization and cCTA on a segmental basis. cCTA had 98% sensitivity, 88% specificity and 92% accuracy for detection of >50% stenosis. DECT detected myocardial ischemia with 84% sensitivity, 94% specificity and 92% accuracy. Our initial experience may warrant further exploration of DECT as a possibly feasible single imaging investigation for the comprehensive diagnosis of coronary stenosis and myocardial ischemia. |
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Geographical breakdown
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United States | 2 | 2% |
Tunisia | 1 | 1% |
Japan | 1 | 1% |
Germany | 1 | 1% |
Unknown | 85 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 25 | 27% |
Student > Ph. D. Student | 15 | 16% |
Other | 8 | 9% |
Professor | 6 | 7% |
Student > Postgraduate | 6 | 7% |
Other | 20 | 22% |
Unknown | 12 | 13% |
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Medicine and Dentistry | 34 | 37% |
Engineering | 12 | 13% |
Physics and Astronomy | 11 | 12% |
Agricultural and Biological Sciences | 6 | 7% |
Computer Science | 4 | 4% |
Other | 8 | 9% |
Unknown | 17 | 18% |