Title |
Correlative and Dynamic Imaging of the Hatching Biology of Schistosoma japonicum from Eggs Prepared by High Pressure Freezing
|
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Published in |
PLoS Neglected Tropical Diseases, November 2008
|
DOI | 10.1371/journal.pntd.0000334 |
Pubmed ID | |
Authors |
Malcolm K. Jones, Sze How Bong, Kathryn M. Green, Philadelphia Holmes, Mary Duke, Alex Loukas, Donald P. McManus |
Abstract |
Schistosome eggs must traverse tissues of the intestine or bladder to escape the human host and further the life cycle. Escape from host tissues is facilitated by secretion of immuno-reactive molecules by eggs and the formation of an intense strong granulomatous response by the host which acts to exclude the egg into gut or bladder lumens. Schistosome eggs hatch on contact with freshwater, but the mechanisms of activation and hatching are poorly understood. In view of the lack of knowledge of the behaviour of egg hatching in schistosomes, we undertook a detailed dynamic and correlative study of the hatching biology of Schistosoma japonicum. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Uruguay | 1 | 2% |
Unknown | 47 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 17% |
Student > Master | 7 | 15% |
Researcher | 6 | 13% |
Professor | 4 | 8% |
Student > Postgraduate | 4 | 8% |
Other | 9 | 19% |
Unknown | 10 | 21% |
Readers by discipline | Count | As % |
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Business, Management and Accounting | 1 | 2% |
Other | 4 | 8% |
Unknown | 10 | 21% |