Title |
Blastocystis hominis and Dientamoeba fragilis in patients fulfilling irritable bowel syndrome criteria
|
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Published in |
Parasitology Research, June 2010
|
DOI | 10.1007/s00436-010-1918-7 |
Pubmed ID | |
Authors |
Javed Yakoob, Wasim Jafri, Mohammad Asim Beg, Zaigham Abbas, Shagufta Naz, Muhammad Islam, Rustam Khan |
Abstract |
Studies have suggested a possible role for Blastocystis hominis and Dientamoeba fragilis in the etiology of irritable bowel syndrome (IBS). We studied the prevalence of B. hominis and D. fragilis in patients with IBS-diarrhea (IBS-D). Three hundred and thirty patients were enrolled, 171 (52%) with IBS-D and 159 (48%) were controls, respectively. Stool microscopy, culture, and polymerase chain reaction (PCR) for B. hominis and D. fragilis were done. B. hominis was positive by stool microscopy in 49% (83/171) of IBS compared to 24% (27/159) in control (p < 0.001). B. hominis culture was positive in 53% (90/171) in IBS compared to 16% (25/159) in control (p < 0.001). B. hominis PCR was positive in 44% (75/171) in IBS compared to 21% (33/159) in control (p < 0.001). D. fragilis microscopy was positive in 3.5% (6/171) in IBS-D compared to 0.6% (1/159) in control (p = 0.123). D. fragilis culture was positive in 4% (7/171) in IBS compared to 1.3% (2/159) in control (p = 0.176). D. fragilis PCR was positive in 4% (6/171) in IBS-D compared to 0% (0/159) in control (p = 0.030). B. hominis is common, while D. fragilis was less prevalent in our patients with IBS-D. B. hominis and D. fragilis culture had a better yield compared to stool microscopy and PCR. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | <1% |
United States | 1 | <1% |
Ecuador | 1 | <1% |
Canada | 1 | <1% |
Unknown | 100 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 19 | 18% |
Student > Bachelor | 17 | 16% |
Student > Master | 16 | 15% |
Student > Ph. D. Student | 9 | 9% |
Professor > Associate Professor | 6 | 6% |
Other | 20 | 19% |
Unknown | 17 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 38% |
Agricultural and Biological Sciences | 17 | 16% |
Biochemistry, Genetics and Molecular Biology | 7 | 7% |
Nursing and Health Professions | 6 | 6% |
Veterinary Science and Veterinary Medicine | 4 | 4% |
Other | 15 | 14% |
Unknown | 15 | 14% |