| Title |
The Epidemiology of Corticosteroid-Induced Osteoporosis: a Meta-analysis
|
|---|---|
| Published in |
Osteoporosis International, October 2002
|
| DOI | 10.1007/s001980200108 |
| Pubmed ID | |
| Authors |
T. P. van Staa, T. P. van Staa, T. P. van Staa, H. G. M. Leufkens, C. Cooper |
| Abstract |
Studies of oral corticosteroid dose and loss of bone mineral density have reported inconsistent results. In this meta-analysis, we used information from 66 papers on bone density and 23 papers on fractures to examine the effects of oral corticosteroids on bone mineral density and risk of fracture. Strong correlations were found between cumulative dose and loss of bone mineral density and between daily dose and risk of fracture. The risk of fracture was found to increase rapidly after the start of oral corticosteroid therapy (within 3 to 6 months) and decrease after stopping therapy. The risk remained independent of underlying disease, age and gender. We conclude that oral corticosteroid treatment using more than 5 mg (of prednisolone or equivalent) daily leads to a reduction in bone mineral density and a rapid increase in the risk of fracture during the treatment period. Early use of preventive measures against corticosteroid-induced osteoporosis is recommended. |
X Demographics
The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 4 | 20% |
| Korea, Republic of | 1 | 5% |
| Unknown | 15 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 20 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 375 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 3 | <1% |
| Canada | 2 | <1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Greece | 1 | <1% |
| Unknown | 367 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 45 | 12% |
| Student > Bachelor | 44 | 12% |
| Student > Ph. D. Student | 34 | 9% |
| Student > Postgraduate | 33 | 9% |
| Student > Master | 31 | 8% |
| Other | 99 | 26% |
| Unknown | 89 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 171 | 46% |
| Biochemistry, Genetics and Molecular Biology | 17 | 5% |
| Agricultural and Biological Sciences | 14 | 4% |
| Nursing and Health Professions | 11 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 3% |
| Other | 46 | 12% |
| Unknown | 106 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 September 2022.
All research outputs
#1,098,394
of 25,652,464 outputs
Outputs from Osteoporosis International
#140
of 3,875 outputs
Outputs of similar age
#896
of 49,918 outputs
Outputs of similar age from Osteoporosis International
#1
of 4 outputs
Altmetric has tracked 25,652,464 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,875 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 49,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them