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X Demographics
Mendeley readers
Attention Score in Context
| Title |
An assessment of histone-modification antibody quality
|
|---|---|
| Published in |
Nature Structural & Molecular Biology, December 2010
|
| DOI | 10.1038/nsmb.1972 |
| Pubmed ID | |
| Authors |
Thea A Egelhofer, Aki Minoda, Sarit Klugman, Kyungjoon Lee, Paulina Kolasinska-Zwierz, Artyom A Alekseyenko, Ming-Sin Cheung, Daniel S Day, Sarah Gadel, Andrey A Gorchakov, Tingting Gu, Peter V Kharchenko, Samantha Kuan, Isabel Latorre, Daniela Linder-Basso, Ying Luu, Queminh Ngo, Marc Perry, Andreas Rechtsteiner, Nicole C Riddle, Yuri B Schwartz, Gregory A Shanower, Anne Vielle, Julie Ahringer, Sarah C R Elgin, Mitzi I Kuroda, Vincenzo Pirrotta, Bing Ren, Susan Strome, Peter J Park, Gary H Karpen, R David Hawkins, Jason D Lieb |
| Abstract |
We have tested the specificity and utility of more than 200 antibodies raised against 57 different histone modifications in Drosophila melanogaster, Caenorhabditis elegans and human cells. Although most antibodies performed well, more than 25% failed specificity tests by dot blot or western blot. Among specific antibodies, more than 20% failed in chromatin immunoprecipitation experiments. We advise rigorous testing of histone-modification antibodies before use, and we provide a website for posting new test results (http://compbio.med.harvard.edu/antibodies/). |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 3 | 75% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 559 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 2% |
| United Kingdom | 8 | 1% |
| France | 4 | <1% |
| Italy | 3 | <1% |
| Spain | 3 | <1% |
| Netherlands | 2 | <1% |
| Germany | 2 | <1% |
| Czechia | 2 | <1% |
| Switzerland | 1 | <1% |
| Other | 7 | 1% |
| Unknown | 514 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 166 | 30% |
| Researcher | 154 | 28% |
| Student > Master | 43 | 8% |
| Student > Bachelor | 31 | 6% |
| Student > Doctoral Student | 28 | 5% |
| Other | 91 | 16% |
| Unknown | 46 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 296 | 53% |
| Biochemistry, Genetics and Molecular Biology | 112 | 20% |
| Medicine and Dentistry | 23 | 4% |
| Chemistry | 22 | 4% |
| Computer Science | 15 | 3% |
| Other | 36 | 6% |
| Unknown | 55 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 33. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2023.
All research outputs
#1,212,700
of 25,718,113 outputs
Outputs from Nature Structural & Molecular Biology
#450
of 4,223 outputs
Outputs of similar age
#5,676
of 192,451 outputs
Outputs of similar age from Nature Structural & Molecular Biology
#1
of 42 outputs
Altmetric has tracked 25,718,113 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,223 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,451 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.