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Attention Score in Context
| Title |
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
|
|---|---|
| Published in |
Nature Genetics, April 2008
|
| DOI | 10.1038/ng.145 |
| Pubmed ID | |
| Authors |
Sheila A Fisher, Mark Tremelling, Carl A Anderson, Rhian Gwilliam, Suzannah Bumpstead, Natalie J Prescott, Elaine R Nimmo, Dunecan Massey, Carlo Berzuini, Christopher Johnson, Jeffrey C Barrett, Fraser R Cummings, Hazel Drummond, Charlie W Lees, Clive M Onnie, Catherine E Hanson, Katarzyna Blaszczyk, Mike Inouye, Philip Ewels, Radhi Ravindrarajah, Andrew Keniry, Sarah Hunt, Martyn Carter, Nick Watkins, Willem Ouwehand, Cathryn M Lewis, Lon Cardon, Alan Lobo, Alastair Forbes, Jeremy Sanderson, Derek P Jewell, John C Mansfield, Panos Deloukas, Christopher G Mathew, Miles Parkes, Jack Satsangi |
| Abstract |
We report results of a nonsynonymous SNP scan for ulcerative colitis and identify a previously unknown susceptibility locus at ECM1. We also show that several risk loci are common to ulcerative colitis and Crohn's disease (IL23R, IL12B, HLA, NKX2-3 and MST1), whereas autophagy genes ATG16L1 and IRGM, along with NOD2 (also known as CARD15), are specific for Crohn's disease. These data provide the first detailed illustration of the genetic relationship between these common inflammatory bowel diseases. |
Mendeley readers
The data shown below were compiled from readership statistics for 275 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 2% |
| United States | 5 | 2% |
| Germany | 3 | 1% |
| Australia | 1 | <1% |
| Chile | 1 | <1% |
| Brazil | 1 | <1% |
| France | 1 | <1% |
| Unknown | 257 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 66 | 24% |
| Student > Ph. D. Student | 53 | 19% |
| Student > Master | 27 | 10% |
| Professor > Associate Professor | 21 | 8% |
| Professor | 20 | 7% |
| Other | 59 | 21% |
| Unknown | 29 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 86 | 31% |
| Medicine and Dentistry | 72 | 26% |
| Biochemistry, Genetics and Molecular Biology | 36 | 13% |
| Immunology and Microbiology | 19 | 7% |
| Computer Science | 6 | 2% |
| Other | 21 | 8% |
| Unknown | 35 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2008.
All research outputs
#15,240,835
of 22,660,862 outputs
Outputs from Nature Genetics
#6,676
of 7,173 outputs
Outputs of similar age
#67,618
of 79,982 outputs
Outputs of similar age from Nature Genetics
#61
of 65 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,173 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 40.9. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 79,982 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.