| Title |
Osteoarthritis and Risk of Fractures
|
|---|---|
| Published in |
Calcified Tissue International, February 2009
|
| DOI | 10.1007/s00223-009-9224-z |
| Pubmed ID | |
| Authors |
Peter Vestergaard, Lars Rejnmark, Leif Mosekilde |
| Abstract |
We conducted a case-control study on the effects of osteoarthritis (OA) on the risk of fractures. There were 124,655 fracture cases and 373,962 age- and gender-matched controls. The main exposure was OA, and the main confounders were use of diuretics, antihypertensive drugs, and pain medication. OA was associated with a decreased risk of any fracture and of hip, forearm, and spine fractures. In general a decreasing trend in the risk of fractures was present with increasing time sine diagnosis of OA. The effect on fractures in areas rich in cortical bone such as the hip in general was larger than effects on skeletal sites rich in trabecular bone such as the spine. OA in the hip and knee, in general, was associated with a decreasing risk of fractures with time since diagnosis of OA, while this was not the case for OA in other locations. OA seems to be associated with a decreased risk of fractures at multiple skeletal sites as well as sites far from the location of OA. This may indicate systemic effects on bone strength, especially in areas rich in cortical bone. |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | 3% |
| United Kingdom | 1 | 3% |
| United States | 1 | 3% |
| Norway | 1 | 3% |
| Unknown | 36 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 25% |
| Researcher | 4 | 10% |
| Professor > Associate Professor | 4 | 10% |
| Student > Doctoral Student | 3 | 8% |
| Student > Bachelor | 3 | 8% |
| Other | 8 | 20% |
| Unknown | 8 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 40% |
| Agricultural and Biological Sciences | 4 | 10% |
| Engineering | 4 | 10% |
| Nursing and Health Professions | 2 | 5% |
| Social Sciences | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 10 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2009.
All research outputs
#15,240,835
of 22,660,862 outputs
Outputs from Calcified Tissue International
#1,335
of 1,755 outputs
Outputs of similar age
#79,649
of 94,227 outputs
Outputs of similar age from Calcified Tissue International
#4
of 5 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,755 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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