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Geographical genomics of human leukocyte gene expression variation in southern Morocco

Overview of attention for article published in Nature Genetics, December 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (51st percentile)

Mentioned by

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11 X users
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1 Wikipedia page
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1 research highlight platform

Citations

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136 Dimensions

Readers on

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146 Mendeley
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3 CiteULike
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1 Connotea
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Title
Geographical genomics of human leukocyte gene expression variation in southern Morocco
Published in
Nature Genetics, December 2009
DOI 10.1038/ng.495
Pubmed ID
Authors

Youssef Idaghdour, Wendy Czika, Kevin V Shianna, Sang H Lee, Peter M Visscher, Hilary C Martin, Kelci Miclaus, Sami J Jadallah, David B Goldstein, Russell D Wolfinger, Greg Gibson

Abstract

Studies of the genetics of gene expression can identify expression SNPs (eSNPs) that explain variation in transcript abundance. Here we address the robustness of eSNP associations to environmental geography and population structure in a comparison of 194 Arab and Amazigh individuals from a city and two villages in southern Morocco. Gene expression differed between pairs of locations for up to a third of all transcripts, with notable enrichment of transcripts involved in ribosomal biosynthesis and oxidative phosphorylation. Robust associations were observed in the leukocyte samples: cis eSNPs (P < 10(-08)) were identified for 346 genes, and trans eSNPs (P < 10(-11)) for 10 genes. All of these associations were consistent both across the three sample locations and after controlling for ancestry and relatedness. No evidence of large-effect trans-acting mediators of the pervasive environmental influence was found; instead, genetic and environmental factors acted in a largely additive manner.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
United Kingdom 2 1%
Chile 1 <1%
Ireland 1 <1%
Israel 1 <1%
Netherlands 1 <1%
Mexico 1 <1%
Australia 1 <1%
Unknown 135 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 40 27%
Student > Ph. D. Student 35 24%
Professor > Associate Professor 10 7%
Student > Doctoral Student 10 7%
Professor 10 7%
Other 29 20%
Unknown 12 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 71 49%
Biochemistry, Genetics and Molecular Biology 26 18%
Medicine and Dentistry 16 11%
Neuroscience 4 3%
Business, Management and Accounting 2 1%
Other 14 10%
Unknown 13 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2023.
All research outputs
#3,582,095
of 25,481,734 outputs
Outputs from Nature Genetics
#3,691
of 7,584 outputs
Outputs of similar age
#17,994
of 176,814 outputs
Outputs of similar age from Nature Genetics
#25
of 49 outputs
Altmetric has tracked 25,481,734 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,584 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 176,814 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.