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Mendeley readers
Attention Score in Context
| Title |
Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses
|
|---|---|
| Published in |
British Medical Journal, July 2000
|
| DOI | 10.1136/bmj.321.7255.199 |
| Pubmed ID | |
| Authors |
John Danesh, Peter Whincup, Mary Walker, Lucy Lennon, Andrew Thomson, Paul Appleby, J Ruth Gallimore, Mark B Pepys |
| Abstract |
To assess associations between baseline values of four different circulating markers of inflammation and future risk of coronary heart disease, potential triggers of systemic inflammation (such as persistent infection), and other markers of inflammation. Nested case-control comparisons in a prospective, population based cohort. General practices in 18 towns in Britain. 506 men who died from coronary heart disease or had a non-fatal myocardial infarction and 1025 men who remained free of such disease until 1996 selected from 5661 men aged 40-59 years who provided blood samples in 1978-1980. Plasma concentrations of C reactive protein, serum amyloid A protein, and serum albumin and leucocyte count. Information on fatal and non-fatal coronary heart disease was obtained from medical records and death certificates. Compared with men in the bottom third of baseline measurements of C reactive protein, men in the top third had an odds ratio for coronary heart disease of 2.13 (95% confidence interval 1.38 to 3.28) after age, town, smoking, vascular risk factors, and indicators of socioeconomic status were adjusted for. Similar adjusted odds ratios were 1.65 (1.07 to 2.55) for serum amyloid A protein; 1.12 (0.71 to 1.77) for leucocyte count; and 0.67 (0.43 to 1.04) for albumin. No strong associations were observed of these factors with Helicobacter pylori seropositivity, Chlamydia pneumoniae IgG titres, or plasma total homocysteine concentrations. Baseline values of the acute phase reactants were significantly associated with one another (P<0.0001), although the association between low serum albumin concentration and leucocyte count was weaker (P=0.08). In the context of results from other relevant studies these findings suggest that some inflammatory processes, unrelated to the chronic infections studied here, are likely to be involved in coronary heart disease. |
Mendeley readers
The data shown below were compiled from readership statistics for 399 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Australia | 2 | <1% |
| Brazil | 2 | <1% |
| United Kingdom | 2 | <1% |
| Spain | 2 | <1% |
| New Zealand | 1 | <1% |
| Indonesia | 1 | <1% |
| Canada | 1 | <1% |
| Russia | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 385 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 64 | 16% |
| Researcher | 55 | 14% |
| Student > Master | 49 | 12% |
| Other | 32 | 8% |
| Student > Bachelor | 31 | 8% |
| Other | 104 | 26% |
| Unknown | 64 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 166 | 42% |
| Agricultural and Biological Sciences | 28 | 7% |
| Biochemistry, Genetics and Molecular Biology | 27 | 7% |
| Nursing and Health Professions | 19 | 5% |
| Psychology | 12 | 3% |
| Other | 59 | 15% |
| Unknown | 88 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 55. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2023.
All research outputs
#763,597
of 25,394,764 outputs
Outputs from British Medical Journal
#8,197
of 64,480 outputs
Outputs of similar age
#374
of 39,005 outputs
Outputs of similar age from British Medical Journal
#14
of 181 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 64,480 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 39,005 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 181 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.