Title |
Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference
|
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Published in |
Annals of Neurology, October 2004
|
DOI | 10.1002/ana.410410606 |
Pubmed ID | |
Authors |
Norman L. Foster, Kirk Wilhelmsen, Anders A. F. Sima, Margaret Z. Jones, Constance J. D'Amato, Sid Gilman, Conference Participants |
Abstract |
We held an international consensus conference on frontotemporal dementia, behavioral disturbances, and parkinsonism linked to chromosome 17 to determine whether these are homogeneous or heterogeneous disorders, to agree on terminology, and to develop strategies for further research. The group identified 13 kindreds with sufficient evidence for linkage, finding in common to all a critical 2 cM between markers D17S791 and D17S800. There was agreement that (1) despite previous descriptions that have emphasized one or another clinical or neuropathological feature, the kindreds share clinical and neuropathological features; (2) until more specific information about the genetic defects becomes available, this disorder is best termed frontotemporal dementia and parkinsonism linked to chromosome 17; and (3) further research will be enhanced by identifying the gene or genes responsible for this disorder, detecting additional cases within known families and, in new families, correlating mutations with phenotypes and more fully delineating the clinical, neuropsychological, and neuropathological characteristics of this disorder. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Spain | 1 | <1% |
Philippines | 1 | <1% |
Germany | 1 | <1% |
Unknown | 102 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 30 | 28% |
Researcher | 12 | 11% |
Student > Master | 9 | 8% |
Student > Doctoral Student | 9 | 8% |
Student > Bachelor | 8 | 7% |
Other | 24 | 22% |
Unknown | 15 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 22% |
Medicine and Dentistry | 23 | 21% |
Neuroscience | 21 | 20% |
Biochemistry, Genetics and Molecular Biology | 9 | 8% |
Psychology | 3 | 3% |
Other | 8 | 7% |
Unknown | 19 | 18% |