| Title |
A dietary pattern derived to correlate with estrogens and risk of postmenopausal breast cancer
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, January 2012
|
| DOI | 10.1007/s10549-011-1942-z |
| Pubmed ID | |
| Authors |
Teresa T. Fung, Matthias B. Schulze, Frank B. Hu, Susan E. Hankinson, Michelle D. Holmes |
| Abstract |
Circulating estrogens are an established risk factor for breast cancer and some data suggest that diet may influence estrogen levels. Therefore, using a subsample (n = 550) of women from a large cohort, we applied reduced rank regression to identify a dietary pattern that was correlated with estradiol and estrone sulfate. We then adapted the pattern to be used with the full cohort (n = 67,802) and prospectively assessed its association with postmenopausal breast cancer. The estrogen food pattern, characterized by higher intakes of red meat, legumes, and pizza, but lower intakes of coffee and whole grains, was modestly but significantly correlated with estradiol (r = 0.14) and estrone sulfate (r = 0.20). During 22 years of follow-up, we ascertained 4,596 incident breast cancer, with 2,938 estrogen receptor-positive tumors and 689 estrogen receptor-negative tumors. However, after adjusting for potential confounders, we did not observe any association with overall estrogen receptor-positive or estrogen receptor-negative breast cancer. In conclusion, diet pattern appeared to only have modest association with estrogens, and was not associated with postmenopausal breast cancer risk. Although these results were null, it should be repeated in other populations as differences in food intake may yield a dietary pattern with stronger association with estrogens. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 19% |
| Student > Bachelor | 10 | 16% |
| Student > Ph. D. Student | 10 | 16% |
| Unspecified | 5 | 8% |
| Student > Postgraduate | 4 | 6% |
| Other | 9 | 14% |
| Unknown | 13 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 22% |
| Agricultural and Biological Sciences | 10 | 16% |
| Nursing and Health Professions | 6 | 10% |
| Unspecified | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 4 | 6% |
| Other | 10 | 16% |
| Unknown | 14 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2022.
All research outputs
#18,298,940
of 23,504,694 outputs
Outputs from Breast Cancer Research and Treatment
#3,628
of 4,728 outputs
Outputs of similar age
#192,426
of 245,015 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#44
of 55 outputs
Altmetric has tracked 23,504,694 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,728 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 245,015 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.