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Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1

Overview of attention for article published in CNS Oncology, November 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Citations

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51 Dimensions

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47 Mendeley
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Title
Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1
Published in
CNS Oncology, November 2015
DOI 10.2217/cns.15.32
Pubmed ID
Authors

Daniel P Cahill, David N Louis, John Gregory Cairncross

Abstract

Oligodendroglioma is the quintessential molecularly-defined brain tumor. The characteristic whole-arm loss of the long arm of chromosome 1 and the short arm of chromosome 19 (1p/19q-codeletion) within the genome of these tumors facilitated the reproducible molecular identification of this subcategory of gliomas. More recently, recurrent molecular genetic alterations have been identified to occur concurrently with 1p/19q-codeletion, and definitively identify these tumors, including mutations in IDH1/2, CIC, FUBP1, and the TERT promoter, as well as the absence of ATRX and TP53 alterations. These findings provide a foundation for the consistent diagnosis of this tumor type, upon which a generation of clinical investigators have assembled a strong evidence base for the effective treatment of this disease with radiation and chemotherapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 21%
Student > Ph. D. Student 6 13%
Student > Doctoral Student 5 11%
Student > Master 3 6%
Student > Postgraduate 3 6%
Other 7 15%
Unknown 13 28%
Readers by discipline Count As %
Medicine and Dentistry 14 30%
Biochemistry, Genetics and Molecular Biology 11 23%
Agricultural and Biological Sciences 2 4%
Neuroscience 2 4%
Immunology and Microbiology 1 2%
Other 1 2%
Unknown 16 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2016.
All research outputs
#14,473,281
of 25,373,627 outputs
Outputs from CNS Oncology
#78
of 193 outputs
Outputs of similar age
#135,597
of 297,292 outputs
Outputs of similar age from CNS Oncology
#6
of 13 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.0. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,292 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.