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Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

Overview of attention for article published in Mechanisms of Ageing & Development, February 2016
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  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921
Published in
Mechanisms of Ageing & Development, February 2016
DOI 10.1016/j.mad.2016.02.004
Pubmed ID
Authors

Sarah E. Harris, Riccardo E. Marioni, Carmen Martin-Ruiz, Alison Pattie, Alan J. Gow, Simon R. Cox, Janie Corley, Thomas von Zglinicki, John M. Starr, Ian J. Deary

Abstract

Telomere length is hypothesised to be a biological marker of both cognitive and physical ageing. Here we measure telomere length, and cognitive and physical abilities at mean ages 70, 73 and 76 years in the Lothian Birth Cohort 1936 (LBC1936), and at mean ages 79, 87, 90 and 92 years in the Lothian Birth Cohort 1921 (LBC1921). We investigate whether telomere length change predicts change in cognitive and physical abilities. In LBC1936 telomere length decreased by an average of 65 base pairs per year and in LBC1921 by 69 base pairs per year. However, change in telomere length did not predict change in cognitive or physical abilities. This study shows that, although cognitive ability, walking speed, lung function and grip strength all decline with age, they do so independently of telomere length shortening.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 109 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 16%
Student > Ph. D. Student 16 15%
Researcher 15 14%
Other 9 8%
Professor 6 6%
Other 18 17%
Unknown 28 26%
Readers by discipline Count As %
Psychology 20 18%
Biochemistry, Genetics and Molecular Biology 13 12%
Medicine and Dentistry 13 12%
Agricultural and Biological Sciences 6 6%
Sports and Recreations 3 3%
Other 16 15%
Unknown 38 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2018.
All research outputs
#6,458,458
of 25,766,791 outputs
Outputs from Mechanisms of Ageing & Development
#503
of 1,511 outputs
Outputs of similar age
#97,122
of 412,114 outputs
Outputs of similar age from Mechanisms of Ageing & Development
#8
of 27 outputs
Altmetric has tracked 25,766,791 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,511 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 412,114 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.